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LACTOPRES:Study on the Effect of Dairy Peptides on Blood Pressure in Untreated Hypertensive Subjects.

This study has been completed.
Unilever R&D
Information provided by:
Wageningen University Identifier:
First received: September 12, 2005
Last updated: May 23, 2008
Last verified: May 2008
Hypertension is an increasingly important medical and public health issue. Literature suggests that there may be a role for dairy foods in the prevention and treatment of hypertension. Recently, it has been suggested that several peptides in milk proteins could have blood pressure lowering properties. LACTOPRES is a randomised, double-blind parallel trial to assess the blood pressure effect of an increased intake of dairy peptides in humans.

Condition Intervention Phase
Behavioral: dairy peptides
Phase 2

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double-Blind
Primary Purpose: Prevention
Official Title: LACTOPRES:Study on the Effect of Dairy Peptides on Blood Pressure in Untreated Hypertensive Subjects.

Further study details as provided by Wageningen University:

Primary Outcome Measures:
  • Blood pressure

Estimated Enrollment: 135
Study Start Date: June 2004
Study Completion Date: June 2005
Primary Completion Date: June 2005 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   35 Years to 70 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • systolic blood pressure >= 140 mmHg
  • BMI between 18 and 32 kg/m2
  • apparently healthy

Exclusion Criteria:

  • antihypertensive medication
  • medically prescribed or slimming diet
  • lactating, pregnant
  • irregular pulse
  Contacts and Locations
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Please refer to this study by its identifier: NCT00167869

Wageningen University, Division of Human Nutrition
Wageningen, Netherlands, 6700 EV
Sponsors and Collaborators
Wageningen University
Unilever R&D
Principal Investigator: Frans J Kok, PhD Wageningen University - Division of Human Nutrition
  More Information

Additional Information: Identifier: NCT00167869     History of Changes
Other Study ID Numbers: METC-WU 04/04
Study First Received: September 12, 2005
Last Updated: May 23, 2008

Keywords provided by Wageningen University:
blood pressure
dairy peptides
bioactive peptides
randomized controlled trial

Additional relevant MeSH terms:
Vascular Diseases
Cardiovascular Diseases processed this record on May 23, 2017