A Trial of Erbitux for Recurrent and Metastatic Mucinous Gastrointestinal Adenocarcinoma Involving the Peritoneal Surfaces
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|ClinicalTrials.gov Identifier: NCT00162110|
Recruitment Status : Completed
First Posted : September 13, 2005
Last Update Posted : October 28, 2015
|Condition or disease||Intervention/treatment||Phase|
|Mucinous Gastrointestinal Adenocarcinoma||Drug: cetuximab||Phase 2|
|Study Type :||Interventional (Clinical Trial)|
|Enrollment :||40 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||A Phase II Trial of Erbitux for Recurrent and Metastatic Mucinous Gastrointestinal Adenocarcinoma Involving the Peritoneal Surfaces|
|Study Start Date :||November 2004|
|Actual Primary Completion Date :||January 2007|
|Actual Study Completion Date :||January 2007|
|Active Comparator: 1||
mg, IV, 225 mg/m2, weekly, 4-52 weeks depending on response.
Other Name: Erbitux
- Evaluate the efficacy of Erbitux in the treatment of mucinous gastrointestinal adenocarcinoma involving the peritoneal surfaces based on clinical response rate.
- To evaulate surgically resected tumor specimens of the EGF receptor, mucins 1-6, and anglogenic indices such as vessel counts, VEGF expression, and Ki-67 expression. To evaluate the safety of Erbitux monotherapy in this patient population.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00162110
|United States, New York|
|New York, New York, United States|
|United States, Ohio|
|Cincinnati, Ohio, United States|
|Study Director:||Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST)||Eli Lilly and Company|