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Estimation of Muscle Area and Thickness of Deep Cervical Muscle Contraction During Cervical and Limb Movements

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00155948
Recruitment Status : Completed
First Posted : September 12, 2005
Last Update Posted : December 20, 2005
Information provided by:
National Taiwan University Hospital

Brief Summary:
The purpose of this study is to investigate the validity and reliability of measurement for cervical multifidus using ultrasonography, and to investigate cervical multifidus muscle function by the change pattern of multifidus thickness, and to compare the changes in muscle thickness among different resistance levels (rest, 25%, 50%, 75% and 100%) and different cervical levels (C4, C5 and C6).

Condition or disease

Detailed Description:

Cervical multifidus has specific sensory and motion function. However, it was unclear about muscle architectural change of cervical multifidus during head retraction manoeuvre with progressive resistance. The validity and reliability of measuring cervical multifidus using ultrasonography hasn't been proven.

In the pilot study, thickness, width and area of multifidus were measured at C4, C5 and C6 were measured using MRI and ultrasonography. The limit of agreement and the regression analysis were used to compare the results of two modalities. Besides, muscle thickness was repeatedly measured during the static and head retraction manoeuvre using ultrasonography by the same rater on the same day; the CVw and CVb were used to investigate reliability. In the main study, multifidus architecture measured in twenty asymptomatic subjects (24.3±4.7 yo, 5 women and 15 men) during head retraction manoeuvre with progressive resistance and during relaxation using ultrasonography apparatus with 10MHz linear transducer. ANOVA with repeated measurement and post-hoc analysis were to investigate the difference among different cervical levels and resistance force levels.

The results of the pilot study showed that the limit of agreement was ±0.20 cm and the moderate level of correlation (R2 ranged in 0.42~0.64) for muscle thickness measured between MRI and ultrasonography. For muscle thickness, the CVw values under static and under head retraction against maximum resistance were lower than 10%. In the main study, there was a curvilinear relationship between muscle thickness change and resistance, and the quadratic equations were the proper curves for estimation. There was significant difference of muscle thickness change within 50% of maximum retraction against resistance; and there was no significant difference among three cervical levels. It was suggested that muscle at C6 relaxed more slowly during the period from the beginning of relaxation.

In conclusion, the present study built a valid and reliable method for measuring continuous and dynamic changes of muscle thickness using ultrasonography. The results supported muscle function of cervical multifidus for segmental stability but not for force production.

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Study Type : Observational
Enrollment : 40 participants
Observational Model: Defined Population
Time Perspective: Other
Official Title: Estimation of Muscle Area and Thickness of Deep Cervical Muscle Contraction During Cervical and Limb Movements
Study Start Date : September 2003
Study Completion Date : May 2004

Information from the National Library of Medicine

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Ages Eligible for Study:   20 Years to 40 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • participants without posterior cervical pain within recent 3 months before entry the study

Exclusion Criteria:

  • Posterior cervical pain
  • Surgery over cervical spine

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00155948

Sponsors and Collaborators
National Taiwan University Hospital
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Principal Investigator: Shwu-Fen Wang, Ph.D. School and graduate institute of Physical Therapy, National Taiwan University
Layout table for additonal information Identifier: NCT00155948    
Other Study ID Numbers: 9261701132
First Posted: September 12, 2005    Key Record Dates
Last Update Posted: December 20, 2005
Last Verified: April 2004
Keywords provided by National Taiwan University Hospital:
Cervical Multifidus