Genomewide Screening of Pathological Myopia
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00155753|
Recruitment Status : Unknown
Verified April 2010 by National Taiwan University Hospital.
Recruitment status was: Recruiting
First Posted : September 12, 2005
Last Update Posted : June 9, 2010
|Condition or disease|
High myopia (pathological myopia) is caused by excessive axial elongation that primarily involves the ora-equatorial area and the posterior pole. Peripheral fundus changes and posterior staphyloma formation are ophthalmoscopic evidences of this process. Pathological myopia often accompanied by glaucoma, cataracts, macular degeneration, and retinal detachment, leading to blindness when the damage to the retina is extremely severe. Population and family studies in Chinese have provided evidence for a genetic component to pathologic myopia. Children of myopic parents are more likely to have myopia than are children of nonmyopic parents. The ocular components (axial length, anterior chamber depth, and corneal curvature) and refractive errors of MZ twins are more closely aligned than are those of DZ twins.
Therefore, it is possible to search a potential candidate gene for myopia through the genomic study of pathological myopia.
|Study Type :||Observational|
|Estimated Enrollment :||600 participants|
|Official Title:||Genomewide Screening of Pathological Myopia|
|Study Start Date :||August 2002|
|Estimated Primary Completion Date :||August 2010|
|Estimated Study Completion Date :||August 2010|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00155753
|Contact: Yung-Feng Shih, MD||886-2-23123456 ext firstname.lastname@example.org|
|National Taiwan University Hospital||Recruiting|
|Taipei, Taiwan, 100|
|Contact: Yung-Feng Shih, MD 886-2-23123456 ext 5184 email@example.com|
|Principal Investigator:||Yung-Feng Shih, MD||National Taiwan University Hospiyal|