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Proton Magnetic Resonance Spectroscopy of Normal Breast Tissues in Women Volunteers

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified January 2005 by National Taiwan University Hospital.
Recruitment status was:  Recruiting
Information provided by:
National Taiwan University Hospital Identifier:
First received: September 9, 2005
Last updated: NA
Last verified: January 2005
History: No changes posted
Magnetic resonance spectroscopy (MRS) is a diagnostic technique in MRI that distinguishes various metabolites on the basis of their slightly different chemical shifts or resonance frequencies. The Proton is the most abundant nucleus in the body. We will try to establish the typical proton MRS pattern of normal women breasts to be a guideline for future further investigations.

Breast Neoplasms

Study Type: Observational
Study Design: Observational Model: Defined Population
Primary Purpose: Screening
Time Perspective: Cross-Sectional
Time Perspective: Prospective

Resource links provided by NLM:

Further study details as provided by National Taiwan University Hospital:

Estimated Enrollment: 80
Study Start Date: January 2005
Estimated Study Completion Date: December 2005
Detailed Description:
There are few reports regarding proton MRS in normal female breasts. The fibroglandular tissues and fat are the two major gross components in the breast. The water content in the fibroglandular tissues is much higher than that in the fat. There is still no documented report discussing proton MRS in normal female breasts of premenopausal and postmenopausal women. Our study is to evaluate the proton MRS findings among normal premenopausal and postmenopausal women breasts, to find out if there are statistical differences on the main proton MRS patterns, water and lipid peak intensities and ratios between the two groups.

Ages Eligible for Study:   30 Years and older   (Adult, Senior)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • women age ranged 30 years of age or older, with normal mammograms or ultrasound in recent 3 months

Exclusion Criteria:

  • any women not fulfilling the inclusion criteria
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00155090

Contact: Jane Wang, MD 886-2-23123456 ext 5565

National Taiwan University Hospital Recruiting
Taipei, Taiwan, 100
Contact: Jane Wang, MD    886-2-23123456 ext 5565   
Principal Investigator: Jane Wang, MD         
Sponsors and Collaborators
National Taiwan University Hospital
Principal Investigator: Jane Wang, MD National Taiwan University Hospital
  More Information

Publications: Identifier: NCT00155090     History of Changes
Other Study ID Numbers: 9361700788
Study First Received: September 9, 2005
Last Updated: September 9, 2005

Keywords provided by National Taiwan University Hospital:
Magnetic resonance imaging,
breast disease

Additional relevant MeSH terms:
Breast Neoplasms
Neoplasms by Site
Breast Diseases
Skin Diseases processed this record on September 21, 2017