Phytosterol Supplementation and Cardiovascular Risk
|Study Design:||Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Single Blind
Primary Purpose: Prevention
|Official Title:||Effectiveness of Phytosterol Supplementation on Select Indices of Cardiovascular Risk|
- Ingestion of the supplement will result in reduced LDL cholesterol.
|Study Start Date:||March 2004|
|Estimated Study Completion Date:||August 2005|
This study examined the effects of 2.6 g/d of phytosterol ingestion on LDL cholesterol metabolism. It is expected that this dose will significantly reduce LDL cholesterol after 12 weeks of supplementation.
The study recruited 72 men and women 20-70 years of age with mild hypercholesteremia (>130 mg/dl LDL-C). They were assigned to 1 of 2 groups. Participants ingested the supplement or a placebo for 12 weeks, with an interim assessment at 6 weeks. Participants agreed to maintain current diet, medication, and exercise habits and to not donate blood during the trial.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00153738
|United States, Texas|
|The Cooper Institute|
|Dallas, Texas, United States, 75230|
|Principal Investigator:||Conrad Earnest, PhD||The Cooper Institute|