Standardized Time- and Score-oriented Treatment of Moderate and Severe Atopic Dermatitis
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|ClinicalTrials.gov Identifier: NCT00148746|
Recruitment Status : Completed
First Posted : September 8, 2005
Last Update Posted : June 9, 2010
The study was designed to test the hypothesis whether a standardized, time-and score-oriented treatment following a strict evidence based algorithm is equally effective to a standard treatment regimen for moderate to severe atopic dermatitis.
Study Type: Mono-centre study, patients are blinded, physicians are randomized to either treat study- or controll group
Eligible are patients age 2 years or older with SCORAD >= 20 Duration: 12 Months, study visits every 4 weeks.
Primary endpoint is Difference between Baseline SCORAD and mean SCORAD under treatment.
Secundary endpoints are quality of life, safety and economic burden in both treatment groups.
|Condition or disease||Intervention/treatment||Phase|
|Moderate to Severe Atopic Dermatitis||Drug: Pimecrolimus Drug: Tacrolimus Drug: Prednisolone Drug: Ciclosporin A Drug: Dermatop||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Intervention Model:||Parallel Assignment|
|Official Title:||Standardized Time- and Score-oriented Treatment of Moderate and Severe Atopic Dermatitis|
|Study Start Date :||May 2004|
|Actual Primary Completion Date :||September 2006|
|Actual Study Completion Date :||March 2008|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00148746
|Department of Dermatology, TU Dresden|
|Dresden, Germany, 01307|
|Study Director:||Jochen M Schmitt, MD, MPH||Dpt. of Dermatology, Medical Faculty, Technical University Dresden, Germany|