Comparison of Three Different Strategies to Prevent Propofol Induced Pain During Infusion
The recruitment status of this study is unknown because the information has not been verified recently.
Verified April 2007 by Hospices Civils de Lyon.
Recruitment status was Active, not recruiting
Information provided by:
Hospices Civils de Lyon
First received: September 5, 2005
Last updated: April 26, 2007
Last verified: April 2007
Propofol is a popular intravenous drug to induce anesthesia but it causes local pain with an incidence between 40 and 90%. Three different strategies to prevent propofol induced pain will be studied compared with placebo. Pain will be scored with a four-point scale.
Induction of Total Intravenous General Anesthesia
Drug: kétamine 20mg
Drug: ephedrine 3mg
Drug: lidocaine 40mg
Intervention Model: Parallel Assignment
||Comparison of Three Different Strategies to Prevent Propofol Induced Pain During Infusion
Primary Outcome Measures:
- After prophylactic solution, evaluation of the pain caused by injection of propofol with a four-point scale before lose of consciousness
Secondary Outcome Measures:
- Explicite and implicite memory of pain immediately after surgery and on day one
- Adverse effects
| Estimated Enrollment:
| Study Start Date:
|Ages Eligible for Study:
||18 Years to 75 Years
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
Healthy adults (ASA 1-2) for scheduled surgery under general anesthesia with propofol
- sedative or analgesic drug 24h before surgery
- allergy with drug used in the study
- difficulty of communication
- absence of informed written consent
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00146926
|Lyon, France, 69495 |
Hospices Civils de Lyon
||Vincent PIRIOU, MD
||Hospices Civils de Lyon
No publications provided
History of Changes
|Other Study ID Numbers:
|Study First Received:
||September 5, 2005
||April 26, 2007
||France: Afssaps - Agence française de sécurité sanitaire des produits de santé (Saint-Denis)
Keywords provided by Hospices Civils de Lyon:
ClinicalTrials.gov processed this record on February 27, 2015