Do Patients With Colorectal Cancer Understand That Their Family is at Risk?

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00145860
Recruitment Status : Terminated
First Posted : September 5, 2005
Last Update Posted : September 5, 2013
Information provided by (Responsible Party):
University of Chicago

Brief Summary:

The purpose of this study is to assess whether patients with colorectal cancer understand that their first-degree relatives are at increased risk of getting the cancer themselves and therefore should be screened early. Among patients who do understand the risks to their family, we plan to determine who they identify as the source of their information and whether they have acted upon this information and advised family members to be screened. We hypothesize that many patients with colorectal cancer do not have a correct understanding of the risks to their first-degree relatives and the recommendations that they be screened early.

If this hypothesis is shown to be true, it can be used to direct improved and more diligent patient education. This, in turn, will hopefully increase the low screening rates among first-degree relatives, and, thereby, save lives in this high-risk population.

Condition or disease
Colorectal Cancer

Detailed Description:
  1. The primary physician of patients with colorectal cancer will be contacted and asked permission to contact their patient to discuss his or her understanding of familial risk before patient is contacted.
  2. A letter will be sent to all patients prior to being contacted, notifying them that all identifying information will be kept confidential and they may decline to participate at any time.
  3. Patients will be called and asked a series of questions about their understanding of familial risk of colon cancer, the need for early screening and where they learned what they know. If the patient has lacking knowledge they will be educated.
  4. Each patient will be sent informational brochures about colon cancer after the phone survey.
  5. Six months later, the patients will be contacted again and asked a series of questions about their understanding of familial risk of colon cancer and the need for early screening to access how much impact the informational brochures had on their knowledge of cancer risk. Patients will be asked one additional demographic question about the highest level of education that they have completed.

Study Type : Observational
Enrollment : 650 participants
Time Perspective: Prospective
Official Title: Do Patients With Colorectal Cancer Understand That Their Family is at Increased Risk?
Study Start Date : April 2002
Study Completion Date : August 2005

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

Patients who were diagnosed with CRC and received first treatment here or elsewhere and patients who were diagnosed elsewhere and received their first treatment here. All are currently followed here and still alive.

Exclusion Criteria:

Patients in the registry who are not followed here, patients with Familial Adenomatous Polyposis, patients with Hereditary Non-Polyposis Colorectal Cancer, and patients with no siblings or children.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00145860

United States, Illinois
The University of Chicago
Chicago, Illinois, United States, 60637
Sponsors and Collaborators
University of Chicago
Principal Investigator: David Rubin, M.D. University of Chicago

Responsible Party: University of Chicago Identifier: NCT00145860     History of Changes
Other Study ID Numbers: 11589A
First Posted: September 5, 2005    Key Record Dates
Last Update Posted: September 5, 2013
Last Verified: September 2013

Keywords provided by University of Chicago:
Colorectal Cancer

Additional relevant MeSH terms:
Colorectal Neoplasms
Intestinal Neoplasms
Gastrointestinal Neoplasms
Digestive System Neoplasms
Neoplasms by Site
Digestive System Diseases
Gastrointestinal Diseases
Colonic Diseases
Intestinal Diseases
Rectal Diseases