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Urokinase Versus Primary Video-Assisted Thorascopic Surgery for Empyema

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ClinicalTrials.gov Identifier: NCT00144950
Recruitment Status : Completed
First Posted : September 5, 2005
Last Update Posted : September 5, 2005
Sponsor:
Information provided by:
Institute of Child Health

Brief Summary:
This study will compare VATS versus chest drain insertion and urokinase in the treatment of childhood empema by a randomised prospective study.

Condition or disease Intervention/treatment Phase
Empyema Drug: insertion of a chest drain with urokinase instillation Procedure: primary video-assisted thorascopic surgery Phase 1

Study Type : Interventional  (Clinical Trial)
Enrollment : 60 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment

Resource links provided by the National Library of Medicine

Drug Information available for: Urokinase
U.S. FDA Resources




Primary Outcome Measures :
  1. length of hospital stay

Secondary Outcome Measures :
  1. radiological changes at follow up


Information from the National Library of Medicine

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Ages Eligible for Study:   up to 16 Years   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • patients under the age of 16 referred to GOSH for management of empyema

Exclusion Criteria:


Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00144950


Locations
United Kingdom
Great Ormond Street Hospital
London, United Kingdom
Sponsors and Collaborators
Institute of Child Health
Investigators
Principal Investigator: Adam Jaffe, Dr Great Ormond Street Hospital

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
ClinicalTrials.gov Identifier: NCT00144950     History of Changes
Other Study ID Numbers: 02AR04
First Posted: September 5, 2005    Key Record Dates
Last Update Posted: September 5, 2005
Last Verified: September 2005

Additional relevant MeSH terms:
Empyema
Suppuration
Infection
Inflammation
Pathologic Processes