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The Specific Elastance in Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) Patients

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00143468
First Posted: September 2, 2005
Last Update Posted: December 1, 2011
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Davide Chiumello, Policlinico Hospital
  Purpose
The investigators aim to study the specific elastance in ALI/ARDS patients during invasive mechanical ventilation.

Condition Intervention
Acute Lung Injury ARDS Behavioral: mechanical ventilation

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: The Specific Elastance in Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) Patients: Barotrauma and Volutrauma

Resource links provided by NLM:


Further study details as provided by Davide Chiumello, Policlinico Hospital:

Primary Outcome Measures:
  • Specific elastance [ Time Frame: 5 minutes ]

Enrollment: 100
Study Start Date: March 2005
Study Completion Date: May 2008
Primary Completion Date: March 2007 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1
ALI/ARDS patients and healthy subjects
Behavioral: mechanical ventilation
measurement of specific lung elastance during mechanical ventilation

Detailed Description:
In sedated and paralyzed ALI/ARDS patients, we studied the specific elastance and also, we compared the specific elastance to healthy subjects during invasive mechanical ventilation.
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   16 Years to 90 Years   (Child, Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Stable ALI/ARDS patients during invasive mechanical ventilation

Exclusion Criteria:

  • Hemodynamic failure, pneumothorax
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00143468


Locations
Italy
Ospedale policlinico
Milano, Italy, 20122
Sponsors and Collaborators
Policlinico Hospital
Investigators
Principal Investigator: davide chiumello, MD Policlinico Hospital
  More Information

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Davide Chiumello, MD, Policlinico Hospital
ClinicalTrials.gov Identifier: NCT00143468     History of Changes
Other Study ID Numbers: 1160
First Submitted: August 31, 2005
First Posted: September 2, 2005
Last Update Posted: December 1, 2011
Last Verified: November 2011

Keywords provided by Davide Chiumello, Policlinico Hospital:
gas exchange
respiratory mechanics

Additional relevant MeSH terms:
Wounds and Injuries
Respiratory Distress Syndrome, Newborn
Respiratory Distress Syndrome, Adult
Acute Lung Injury
Lung Injury
Lung Diseases
Respiratory Tract Diseases
Respiration Disorders
Infant, Premature, Diseases
Infant, Newborn, Diseases
Thoracic Injuries