Study to Compare the Effect of Treatment With Carbidopa/Levodopa/Entacapone on the Quality of Life of Patients With Parkinson's Disease. This Study is Not Recruiting in the United States
![]() |
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. |
ClinicalTrials.gov Identifier: NCT00143026 |
Recruitment Status :
Completed
First Posted : September 2, 2005
Last Update Posted : March 29, 2017
|
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
Condition or disease | Intervention/treatment | Phase |
---|---|---|
Parkinson's Disease | Drug: carbidopa, levodopa, entacapone | Phase 4 |
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 184 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | Double |
Primary Purpose: | Treatment |
Official Title: | Study to Compare the Effect of Treatment With Carbidopa/Levodopa/Entacapone on the Quality of Life of Patients With Parkinson's Disease. |
Study Start Date : | July 2005 |
Actual Primary Completion Date : | June 2006 |
Actual Study Completion Date : | June 2006 |

- Quality of life assessment
- Symptom control change from baseline
- Change from baseline in number of wearing-off symptoms
- Change from baseline in proportion of patients experiencing wearing-off

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study: | 30 Years and older (Adult, Older Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- Clinical diagnosis of idiopathic Parkinson's disease exhibiting at least 2 or 3 symptoms
- Motor functions must be regarded as non-disabling by the patient
Exclusion Criteria:
- History, signs or symptoms suggesting the diagnosis of atypical or secondary parkinsonism
- History of dyskinesia
- Previous or current use of entacapone or tolcapone
- Unstable Parkinson's disease patients requiring/receiving regimens of levodopa
- Subjects taking levodopa/DDCI controlled release or extended release formulations

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00143026
Australia | |
Royal Adelaide Hospital | |
Adelaide, Australia | |
Watkins Medical Center | |
Brisbane, Australia | |
Central Coast Neuroscience Research | |
Gosford, Australia | |
Heidelberg Repatriation Hospital | |
Melbourne, Australia | |
Monash Medical Centre | |
Melbourne, Australia | |
Sir Charles Gairdner Hospital | |
Perth, Australia | |
Concord Hospital | |
Sydney, Australia | |
Southern Neurology, St. George Private Hospital | |
Sydney, Australia | |
Westmead Hospital | |
Sydney, Australia | |
Philippines | |
St. Luke's Medical Centre | |
Manila, Philippines | |
University of Santo Tomas Hospital | |
Manila, Philippines | |
Taiwan | |
Chang Gung Memorial Hospital | |
Linkou, Taiwan | |
Kaohsiung Medical University, Chung-Ho Memorial Hospital | |
Linkou, Taiwan | |
National Taiwan University Hospital | |
Linkou, Taiwan | |
Thailand | |
King Chulalongkorn Memorial Hospital | |
Bangkok, Thailand | |
Maharaj Nakorn Chiangmai Hospital | |
Bangkok, Thailand | |
Siriraj Hospital | |
Bangkok, Thailand | |
Pharmongkutklao Army Hospital | |
Bankok, Thailand |
Study Chair: | Novartis Pharmaceuticals |
Additional Information:
Responsible Party: | Novartis |
ClinicalTrials.gov Identifier: | NCT00143026 History of Changes |
Other Study ID Numbers: |
CELC200A2406 |
First Posted: | September 2, 2005 Key Record Dates |
Last Update Posted: | March 29, 2017 |
Last Verified: | March 2017 |
Parkinson's disease, levodopa, motor fluctuations |
Parkinson Disease Parkinsonian Disorders Basal Ganglia Diseases Brain Diseases Central Nervous System Diseases Nervous System Diseases Movement Disorders Neurodegenerative Diseases Levodopa Carbidopa Entacapone Carbidopa, levodopa drug combination |
Antiparkinson Agents Anti-Dyskinesia Agents Dopamine Agents Neurotransmitter Agents Molecular Mechanisms of Pharmacological Action Physiological Effects of Drugs Aromatic Amino Acid Decarboxylase Inhibitors Enzyme Inhibitors Catechol O-Methyltransferase Inhibitors Adjuvants, Immunologic Immunologic Factors Dopamine Agonists |