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The Benefit of Adding Fish Oil to the Nutrition of Critically Ill Patients

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ClinicalTrials.gov Identifier: NCT00142220
Recruitment Status : Completed
First Posted : September 2, 2005
Last Update Posted : September 11, 2006
Sponsor:
Collaborator:
Fresenius AG
Information provided by:
University Medicine Greifswald

Brief Summary:
We study whether an increased proportion of omega-3-fatty acids (contained in fish oil) in the nutrition of critically ill patients reduces systemic inflammation.

Condition or disease Intervention/treatment Phase
Sepsis Syndrome Drug: Defined percentage of omega-3-fatty acids Phase 4

Study Type : Interventional  (Clinical Trial)
Enrollment : 160 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double
Primary Purpose: Treatment
Official Title: Comparison Between Two Different Proportions of Omega-3- and Omega-6-Fatty Acids in the Parenteral Nutrition of Critically Ill Patients
Study Start Date : January 2004

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U.S. FDA Resources




Primary Outcome Measures :
  1. level of IL-6 in serum
  2. HLA-expression on monocytes

Secondary Outcome Measures :
  1. number of nosocomial infections
  2. days on mechanical ventilation
  3. duration of ICU stay
  4. mortality
  5. SOFA score


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Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • indication for parenteral nutrition

Exclusion Criteria:

  • hypertriglyceridemia
  • coagulation disorder
  • decompensated liver cirrhosis or acute liver failure

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00142220


Locations
Germany
Internistische ITS
Greifswald, Germany, 17475
Sponsors and Collaborators
University Medicine Greifswald
Fresenius AG
Investigators
Principal Investigator: Sigrun Friesecke, Dr. University Medicine Greifswald

ClinicalTrials.gov Identifier: NCT00142220     History of Changes
Other Study ID Numbers: OMEGAVEN
First Posted: September 2, 2005    Key Record Dates
Last Update Posted: September 11, 2006
Last Verified: September 2006

Additional relevant MeSH terms:
Critical Illness
Systemic Inflammatory Response Syndrome
Toxemia
Sepsis
Disease Attributes
Pathologic Processes
Inflammation
Shock
Infection