The Renin-Angiotensin System in Essential Hypertension
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ClinicalTrials.gov Identifier: NCT00141583
Recruitment Status :
(Insufficient accrual rate)
Although ACE Inhibitors and Angiotensin Receptor Blockers are effective blood pressure lowering agents, the exact mechanisms by which these agents lower BP are still not fully understood. This study aims to compare the blood pressure and hormonal responses (plasma renin activity and aldosterone) to the ACE inhibitor enalapril and ARB candesartan in individuals with mild essential hypertension.
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Ages Eligible for Study:
18 Years to 70 Years (Adult, Senior)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
SBP 140-159 mmHg
DBP 90-99 mmHg
Intolerance of or allergy to ACE Inhibitors or ARBS