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The Effect of Cycling Off Criteria During Pressure Support Ventilation in Chronic Obstructive Pulmonary Disease (COPD) Patients

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ClinicalTrials.gov Identifier: NCT00141440
Recruitment Status : Completed
First Posted : September 1, 2005
Last Update Posted : December 30, 2009
Sponsor:
Information provided by:

Study Description
Brief Summary:
The investigators' aim is to study the effect of cycling off criteria during pressure support ventilation in COPD patients at two levels of PEEP and PSV.

Condition or disease Intervention/treatment
Chronic Obstructive Pulmonary Disease Procedure: mechanical ventilation

Detailed Description:
In this study two levels of cycling off criteria at two levels of PEEP and PSV were tested in term of gas exchange, respiratory mechanics, work of breathing and patient comfort.

Study Design

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 13 participants
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: The Effect of Cycling Off Criteria During Pressure Support Ventilation in Chronic Obstructive Pulmonary Disease (COPD) Patients
Study Start Date : July 2005
Primary Completion Date : March 2007
Study Completion Date : March 2007

Resource links provided by the National Library of Medicine

MedlinePlus related topics: COPD Lung Diseases
U.S. FDA Resources

Arms and Interventions

Arm Intervention/treatment
Experimental: 1
COPD patients
Procedure: mechanical ventilation
evaluated the effect of two different cycling off criteria on breathing pattern, respiratory effort, and gas exchange in patients with chronic obstructive pulmonary disease


Outcome Measures

Primary Outcome Measures :
  1. Respiratory mechanics, gas exchange [ Time Frame: 2 minutes ]

Secondary Outcome Measures :
  1. Comfort of breathing [ Time Frame: 2 minutes ]

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   16 Years to 90 Years   (Child, Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Stable COPD patients during invasive mechanical ventilation

Exclusion Criteria:

  • Hemodynamic instability,
  • Paralysis
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00141440


Locations
Italy
Ospedale Sacco
Milano, Italy, 20100
Sponsors and Collaborators
Policlinico Hospital
Investigators
Principal Investigator: davide chiumello, md Policlinico Hospital
Study Chair: Davide Chiumello, MD Policlinico
More Information

Publications:
Responsible Party: Davide Chiumello, Policlinico Hospital
ClinicalTrials.gov Identifier: NCT00141440     History of Changes
Other Study ID Numbers: 1073
First Posted: September 1, 2005    Key Record Dates
Last Update Posted: December 30, 2009
Last Verified: September 2008

Keywords provided by Policlinico Hospital:
gas exchange
pressure support ventilation
respiratory mechanics
COPD patients

Additional relevant MeSH terms:
Lung Diseases
Lung Diseases, Obstructive
Pulmonary Disease, Chronic Obstructive
Respiratory Tract Diseases