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Trial record 19 of 888 for:    Recruiting, Not yet recruiting, Available Studies | "Neuromuscular Diseases"

Genetics of Cardiovascular and Neuromuscular Disease

This study is currently recruiting participants.
See Contacts and Locations
Verified August 2016 by University of Chicago
Information provided by (Responsible Party):
University of Chicago Identifier:
First received: August 29, 2005
Last updated: August 23, 2016
Last verified: August 2016
We are studying the genetics of human cardiovascular and neuromuscular disease. There are many different genetic regions that have been associated with the development of cardiomyopathy. An equal number of genetic regions have been associated with muscular dystrophy and there is overlap because some of the identical genes, when mutated, produce both cardiomyopathy and muscular dystrophy. We are working to identify genes and gene mutations associated with cardiomyopathy, arrhythmias and muscular dystrophy. We propose to screen these samples for mutations in genes known to be involved in these disorders.

Condition Intervention
Cardiomyopathy Arrhythmia Muscular Dystrophy Procedure: Blood draw (genetic testing)

Study Type: Observational
Study Design: Observational Model: Family-Based
Official Title: Genetic Studies of Patients and Their Families With Inherited Cardiovascular and Neuromuscular Diseases.

Resource links provided by NLM:

Further study details as provided by University of Chicago:

Primary Outcome Measures:
  • Identification of genetic causes of cardiomyopathy [ Time Frame: unlimited ]

Estimated Enrollment: 2000
Study Start Date: September 1996
Estimated Primary Completion Date: January 2025 (Final data collection date for primary outcome measure)
Intervention Details:
    Procedure: Blood draw (genetic testing)
    Blood draw (genetic testing)

Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients of all ages with familial idiopathic cardiomyopathy, including dilated, hypertrophic, and left ventricular non-compaction cardiomyopathy

Inclusion Criteria:

  • Patients of all ages will be considered for the study. In particular, families with more than one affected relative will be sought.

Exclusion Criteria:

  • Subjects without a suspected inherited cardiovascular or neuromuscular disorder will be excluded from this study.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00138931

Contact: Lisa Dellefave, MS 773-702-4310
Contact: Elizabeth McNally, MD PhD 773-702-2679

United States, Illinois
University of Chicago Recruiting
Chicago, Illinois, United States, 60637
Contact: Lisa Dellefave, MS    773-702-4310   
Sponsors and Collaborators
University of Chicago
Principal Investigator: Elizabeth McNally, MD PhD University of Chicago
  More Information

Additional Information:

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: University of Chicago Identifier: NCT00138931     History of Changes
Other Study ID Numbers: 8249
Study First Received: August 29, 2005
Last Updated: August 23, 2016

Keywords provided by University of Chicago:
Muscular Dystrophy

Additional relevant MeSH terms:
Muscular Dystrophies
Neuromuscular Diseases
Heart Diseases
Cardiovascular Diseases
Muscular Disorders, Atrophic
Muscular Diseases
Musculoskeletal Diseases
Nervous System Diseases
Genetic Diseases, Inborn processed this record on September 19, 2017