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Mass Treatment T Solium Community Study

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00138359
Recruitment Status : Terminated
First Posted : August 30, 2005
Last Update Posted : August 27, 2010
Information provided by:
National Institute of Allergy and Infectious Diseases (NIAID)

Brief Summary:
Investigators from Cayetano Heredia University and Johns Hopkins University are doing this study. They want to see how people and pigs get infected with a parasite, called cysticercus (known as "pig triquina"). Cysticercus attacks the meat of pigs and the brains of people. In the intestine, the parasite is known as "solitaria". This study is to see how treatment in both people and pigs works to control the disease.

Condition or disease Intervention/treatment Phase
Intestinal Parasitism Drug: Niclosamide Not Applicable

Detailed Description:
This is a prospective intervention study to determine the efficacy and persistence of effect over time of a single, chemotherapy intervention in both the human and porcine population. Four villages will be selected to be treated against T solium adult (in humans) and larval forms (in pigs), and two villages will receive no intervention and will serve as control villages. Pigs in control villages will be followed during 3 months only, and then the human and porcine populations will receive the intervention treatment. The effect of this intervention will be measured by the prevalence of infection in pigs and parasitic burden of infected pigs at month 3, 6, 9, and 12.

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Study Type : Interventional  (Clinical Trial)
Enrollment : 4200 participants
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: The Effect of a Single Control Intervention in the T Solium Life Cycle
Study Start Date : December 2004
Study Completion Date : January 2005

Resource links provided by the National Library of Medicine

Information from the National Library of Medicine

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Ages Eligible for Study:   2 Years and older   (Child, Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • All consenting individuals older than two years living in the study villages (6 endemic communities of the Northern coast of Peru)

Exclusion Criteria:

  • Pregnancy (for antiparasitic treatment only).

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00138359

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Universidad Peruana Cayetano Heredia
Lima, Peru
Sponsors and Collaborators
National Institute of Allergy and Infectious Diseases (NIAID)

Layout table for additonal information Identifier: NCT00138359     History of Changes
Other Study ID Numbers: 04-043
First Posted: August 30, 2005    Key Record Dates
Last Update Posted: August 27, 2010
Last Verified: December 2006

Keywords provided by National Institute of Allergy and Infectious Diseases (NIAID):
T solium, cysticercus, pig triquina, solitaria, intestinal parasites, Niclosamide, tapeworms, Taeniasis

Additional relevant MeSH terms:
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Intestinal Diseases, Parasitic
Parasitic Diseases
Intestinal Diseases
Gastrointestinal Diseases
Digestive System Diseases
Anticestodal Agents
Antiplatyhelmintic Agents
Antiparasitic Agents
Anti-Infective Agents
Antinematodal Agents