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Effects on the Diagnostic Accuracy of Magnetic Imaging Angiographies of the Supra-Aortic Vessels by Three Different Magnetic Resonance Contrast Agents in Patients

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ClinicalTrials.gov Identifier: NCT00132223
Recruitment Status : Unknown
Verified April 2006 by University Hospital Muenster.
Recruitment status was:  Recruiting
First Posted : August 19, 2005
Last Update Posted : April 12, 2006
Sponsor:
Information provided by:
University Hospital Muenster

Study Description
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Brief Summary:

Angiographies of the supra-aortic vessels by magnetic imaging have become common recently. So it was the purpose of this study to evaluate the imaging potential of different contrast agents.

Three contrast agents for magnetic resonance imaging are compared in angiographies of the supra-aortic arteries in a intraindividual study of 10 patients.

All applications of these contrast agents are performed with a flow of 2 ml/s. One contrast medium is applicated a second time with a reduced flow of 1 ml/s.

The angiographies of the supra-aortic vessels are evaluated by two experienced readers in a consensus reading. The signal/noise- and contrast/noise-ratio of anatomic vessel segments of the carotic and vertebral arteries are measured and compared to each other.


Condition or disease Intervention/treatment Phase
Headache Epilepsy Dizziness Drug: Contrast agent Phase 4

Study Design
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Study Type : Interventional  (Clinical Trial)
Enrollment : 10 participants
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Single
Primary Purpose: Diagnostic
Official Title: Effects on the Diagnostic Accuracy of Magnetic Imaging Angiographies of the Supra-Aortic Vessels by Three Different Magnetic Resonance Contrast Agents in Patients With Headache and Dizziness or Epilepsy and Clinical Indication for an Angiography by Magnetic Imaging
Study Start Date : April 2005
Study Completion Date : December 2005

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Arms and Interventions
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Outcome Measures
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Primary Outcome Measures :
  1. intensity of vessels, muscle, air

Secondary Outcome Measures :
  1. signal/noise ratio
  2. contrast/nose ratio

Eligibility Criteria
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Ages Eligible for Study:   18 Years to 60 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Headache
  • Epilepsia
  • Dizziness

Exclusion Criteria:

  • Pregnancy
  • Metal implants (e.g. pacemaker)
  • Contraindication for contrast agent
  • Multiple allergies
Contacts and Locations
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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00132223


Contacts
Contact: Boris Buerke, MD 00492518345123 buerkeb@uni-muenster.de
Contact: Bernd Tombach, MD 00492518345123 tombach@uni-muenster.de

Locations
Germany
University of Muenster, Dept. of Clinical Radiology Recruiting
Muenster, Germany, 48129
Contact: Boris Buerke, MD    00492518345123    buerkeb@uni-muenster.de   
Contact: Bernd Tombach    00492518345123    tombach@uni-muenster.de   
Principal Investigator: Bernd Tombach, MD         
Sub-Investigator: Boris Buerke, MD         
Sponsors and Collaborators
University Hospital Muenster
Investigators
Study Chair: Bernd Tombach, MD University of Muenster, Dept. of Clinical Radiology
More Information
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Study Description Study Design Arms and Interventions Outcome Measures Eligibility Criteria Contacts and Locations More Information

ClinicalTrials.gov Identifier: NCT00132223     History of Changes
Other Study ID Numbers: 0710/2004-IKR
First Posted: August 19, 2005    Key Record Dates
Last Update Posted: April 12, 2006
Last Verified: April 2006

Keywords provided by University Hospital Muenster:
magnetic imaging
angiography
contrast agent
 signal/noise ratio
contrast/noise ratio
vessel

Additional relevant MeSH terms:
Epilepsy
Headache
Dizziness
Vertigo
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Pain
Neurologic Manifestations
Signs and Symptoms
Sensation Disorders
Vestibular Diseases
Labyrinth Diseases
 Ear Diseases
Otorhinolaryngologic Diseases
Glucuronyl glucosamine glycan sulfate
Anticoagulants
Hypolipidemic Agents
Antimetabolites
Molecular Mechanisms of Pharmacological Action
Lipid Regulating Agents
Fibrinolytic Agents
Fibrin Modulating Agents
Hypoglycemic Agents
Physiological Effects of Drugs