Vitamin D Treatment for Crohn´s Disease
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|ClinicalTrials.gov Identifier: NCT00132184|
Recruitment Status : Unknown
Verified April 2007 by University of Aarhus.
Recruitment status was: Active, not recruiting
First Posted : August 19, 2005
Last Update Posted : April 13, 2007
|Condition or disease||Intervention/treatment||Phase|
|Crohns Disease||Drug: Vitamin D||Phase 2 Phase 3|
Crohns Disease is an inflammatory disease of primarily the small intestine and colon.
In recent years scientists have hypothesized that low blood vitamin-D levels play a role in the development of autoimmune diseases, including Crohns disease. The purpose of this study is to examine whether vitamin-D is effective in keeping remission in inactive Crohns Disease (double blind placebo controlled trial). The patients who have active disease in the placebo group (reach primary endpoint), will in an open setting receive a higher single dose vitamin-D and the effect will be measured within 4 weeks.
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||110 participants|
|Intervention Model:||Parallel Assignment|
|Official Title:||Remission Keeping and Remission Inducing Effect by Vitamin-D in Crohns Disease, and in Vitro Vitamin-D Mediated T-Cell Immunomodulation|
|Study Start Date :||September 2005|
|Estimated Study Completion Date :||February 2008|
- Relapse rate within 1 year treatment; CDAI>220
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00132184
|Aarhus University Hospital, Department V|
|Aarhus, Denmark, 8000|
|Hospital of Horsens|
|Horsens, Denmark, 8700|
|Hospital of Randers|
|Randers, Denmark, 8900|
|Hospital of Silkeborg|
|Silkeborg, Denmark, 8600|
|Principal Investigator:||Jens F. Dahlerup, MD, DrMedSc||Aarhus University Hospital|