Vitamin D Treatment for Crohn´s Disease
Recruitment status was Active, not recruiting
The purpose of this study is to examine whether vitamin D treatment is effective in Crohn's disease.
|Study Design:||Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Primary Purpose: Treatment
|Official Title:||Remission Keeping and Remission Inducing Effect by Vitamin-D in Crohns Disease, and in Vitro Vitamin-D Mediated T-Cell Immunomodulation|
- Relapse rate within 1 year treatment; CDAI>220
|Study Start Date:||September 2005|
|Estimated Study Completion Date:||February 2008|
Crohns Disease is an inflammatory disease of primarily the small intestine and colon.
In recent years scientists have hypothesized that low blood vitamin-D levels play a role in the development of autoimmune diseases, including Crohns disease. The purpose of this study is to examine whether vitamin-D is effective in keeping remission in inactive Crohns Disease (double blind placebo controlled trial). The patients who have active disease in the placebo group (reach primary endpoint), will in an open setting receive a higher single dose vitamin-D and the effect will be measured within 4 weeks.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00132184
|Aarhus University Hospital, Department V|
|Aarhus, Denmark, 8000|
|Hospital of Horsens|
|Horsens, Denmark, 8700|
|Hospital of Randers|
|Randers, Denmark, 8900|
|Hospital of Silkeborg|
|Silkeborg, Denmark, 8600|
|Principal Investigator:||Jens F. Dahlerup, MD, DrMedSc||Aarhus University Hospital|