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Cognitive Therapy Versus Supportive Therapy in Borderline Personality Disorder

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ClinicalTrials.gov Identifier: NCT00131781
Recruitment Status : Unknown
Verified April 2007 by Hospices Civils de Lyon.
Recruitment status was:  Active, not recruiting
First Posted : August 19, 2005
Last Update Posted : April 27, 2007
Sponsor:
Information provided by:
Hospices Civils de Lyon

Study Description
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Brief Summary:

This is a randomised trial comparing cognitive therapy and supportive therapy administered along one year in borderline personality disorder. The follow-up is one year after treatments end.

The therapists were the same in the two groups. Patients received one session a week during six months and one session every two weeks during the next six months


Condition or disease Intervention/treatment Phase
Borderline Personality Disorder Behavioral: Cognitive Therapy Behavioral: Supportive Therapy Not Applicable

Detailed Description:
  • Cognitive Therapy
  • Structured session
  • Conceptualization of the case with the patient
  • Cognitive methods
  • Guided discovery of the schemas
  • Work on life-scenarios
  • From scenarios to schemas
  • Empathic confrontation to the schemas
  • Building new schemas (Core belief work-sheet)
  • Affective methods: role playing
  • Interpersonal methods: counter transference issues
  • Behavioral experiment
  • Problem solving
  • Consolidation methods
  • Patients and therapists had manuals
  • Supportive Therapy
  • Therapist: active listening (face to face)
  • Empathy
  • Unconditional positive regard
  • Reformulation and clarification
  • Reflection of the patient's feelings
  • Reassurance
  • Therapist emphasizes the importance to ventilate problems
  • Therapist answers some factual questions
  • Therapist politely ignore or refuse requests for advice and directive attitudes
  • Therapist demonstrates warmth and genuineness
  • Patients and therapists had manuals
Study Design
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Study Type : Interventional  (Clinical Trial)
Enrollment : 70 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single
Official Title: Cognitive Therapy Versus Supportive Therapy in Borderline Personality Disorder
Study Start Date : March 2001

Resource links provided by the National Library of Medicine


Arms and Interventions
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Outcome Measures
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Primary Outcome Measures :
  1. Clinical Global Impression (CGI): Improvement (1-7): score 3 ( a little better) associated with a hopelessness scale score < 8 (this means that the suicide risk is low)

Secondary Outcome Measures :
  1. CGI severity and improvement
  2. Hamilton depression
  3. Beck Depression Inventory
  4. Hopelessness
  5. Young: Schema Questionnaire II
  6. Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Personality Disorders Personality Questionnaire (SCID II PQ)
  7. Minnesota Multiphasic Personality Inventory (MMPI) (minimult)
  8. Eysenck: impulsivity scale
  9. Checklist: impulsive risky behaviors
  10. Quality of life
  11. Handicap (Sheehan)
  12. Time: Pre test, six months, post test and one year post treatment follow-up
  13. Therapeutic relationship evaluation scale (patients and therapists)

Eligibility Criteria
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Ages Eligible for Study:   18 Years to 65 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Criteria

Inclusion Criteria:

  • DSM-4 DIBR >=8 (Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Diagnostic inventory for borderline-revised)
Contacts and Locations
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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00131781


Locations
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France
Hopital Pierre Wertheimer
Bron, France, 69677
Sponsors and Collaborators
Hospices Civils de Lyon
Investigators
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Principal Investigator: Jean COTTRAUX, MD Hospices Civils de Lyon
More Information
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Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

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ClinicalTrials.gov Identifier: NCT00131781    
Other Study ID Numbers: 2000.230
First Posted: August 19, 2005    Key Record Dates
Last Update Posted: April 27, 2007
Last Verified: April 2007
Keywords provided by Hospices Civils de Lyon:
Borderline personality disorder
Controlled trials
Cognitive Therapy
 Supportive Therapy
suicide
impulsivity
Additional relevant MeSH terms:
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Disease
Personality Disorders
Borderline Personality Disorder
Pathologic Processes
Mental Disorders