Paravertebral Block for Breast Surgery

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00131170
Recruitment Status : Completed
First Posted : August 17, 2005
Last Update Posted : July 6, 2007
Information provided by:
University of Aarhus

Brief Summary:
The effect of paravertebral block in combination with general anaesthesia is studied in a double blind fashion.

Condition or disease Intervention/treatment Phase
Breast Cancer Procedure: paravertebral block Phase 4

Detailed Description:
Patients having surgery for breast cancer receive a paravertebral blockade at C8-Th4 with either Naropin 0.5% or saline. General anaesthesia is then provided with laryngeal mask intubation, propofol infusion and fentanyl i.v. as needed. The effect on postoperative pain ([VAS] and fentanyl PCA doses taken) and postoperative nausea and vomiting is recorded.

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 90 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double
Primary Purpose: Prevention
Study Start Date : September 2005
Actual Study Completion Date : September 2006

Resource links provided by the National Library of Medicine

Primary Outcome Measures :
  1. Nausea and vomiting 2 hours postoperatively, and 1 and 2 days postoperatively [ Time Frame: 2 days ]

Secondary Outcome Measures :
  1. Dosage of analgesic [ Time Frame: 1 day ]

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 85 Years   (Adult, Older Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Breast surgery

Exclusion Criteria:

  • Infections
  • Coagulation disorder
  • Allergy

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00131170

Dept of Anesthesiology, Aarhus University Hospital
Aarhus, Denmark, DK 8000
Sponsors and Collaborators
University of Aarhus
Principal Investigator: Palle Carlsson, MD Dr Sci Dept anesthesiology, Arhus University Hospital Identifier: NCT00131170     History of Changes
Other Study ID Numbers: PVB1
First Posted: August 17, 2005    Key Record Dates
Last Update Posted: July 6, 2007
Last Verified: July 2007