Quality of Life of Adult Cancer Survivors Who Have Undergone a Previous Bone Marrow or Peripheral Stem Cell Transplant for a Childhood Hematologic Cancer
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|ClinicalTrials.gov Identifier: NCT00126477|
Recruitment Status : Completed
First Posted : August 4, 2005
Last Update Posted : May 1, 2013
RATIONALE: Studying quality of life in cancer survivors may help determine the long-term effects of hematologic cancer and may help improve the quality of life for future cancer survivors.
PURPOSE: This clinical trial is studying the quality of life of adult cancer survivors who have undergone a previous bone marrow or peripheral stem cell transplant for a childhood hematologic cancer.
|Condition or disease||Intervention/treatment||Phase|
|Leukemia Lymphoma Myelodysplastic Syndromes Quality of Life||Procedure: cognitive assessment Procedure: management of therapy complications Procedure: psychosocial assessment and care Procedure: quality-of-life assessment||Phase 2|
- Determine the extent to which adult cancer survivors who have undergone prior bone marrow or peripheral blood stem cell transplantation for a pediatric hematologic malignancy require ongoing health care and whether these needs change with increasing time after transplantation.
- Correlate physical capabilities, body image, physical limitations, including sexuality issues which alter or influence lifestyle, with time after transplantation in these patients.
- Determine whether cognitive abilities relative to memory and neurobehavioral ratings change with increasing time after transplantation in these patients.
- Correlate social and relationship abilities with length of time after transplantation in these patients.
OUTLINE: Patients and siblings complete a self-report quality of life questionnaire, including outcome assessments of neuroendocrine function, cognitive abilities, physical capability, and psychosocial behavior.
PROJECTED ACCRUAL: Approximately 750 patients (375 adult cancer survivors [case group] and 375 siblings [control group]) will be accrued for this study within 7 years.
|Study Type :||Observational|
|Estimated Enrollment :||750 participants|
|Official Title:||The Quality of Life of Adult Survivors Who Received a Marrow Transplant as a Child|
|Study Start Date :||March 1996|
|Primary Completion Date :||April 2007|
|Study Completion Date :||March 2010|
- Neuroendocrine status of disease-free childhood transplant patients at 5 years after transplant and ≥ age 18
- Cognitive capability of disease-free childhood transplant patients at 5 years after transplant and ≥ age 18
- Physical capability of disease-free childhood transplant patients at 5 years after transplant and ≥ age 18
- Psychosocial status of disease-free childhood transplant patients at 5 years after transplant and ≥ age 18
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00126477
|United States, Washington|
|Fred Hutchinson Cancer Research Center|
|Seattle, Washington, United States, 98109-1024|
|Principal Investigator:||Jean E. Sanders, MD||Fred Hutchinson Cancer Research Center|