Sublingual Methadone for the Management of Cancer Breakthrough Pain
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Ages Eligible for Study:
18 Years and older (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
> 18 years of age
Experiences episodes of breakthrough pain which respond to opioid therapy
Controlled baseline pain
Cognitive status sufficient for accurate completion of assessment form
Willing to provide written informed consent
Ability to hold a volume of 1 cc of water under the tongue for 5 minutes
Currently or has received methadone during the previous week
Recent history of substance abuse
Severe respiratory impairment or other contraindications to opioids
Recently received therapies that had the potential to alter pain intensity or response to analgesics