Study Comparing Olanzapine With Haloperidol for the Relief of Nausea and Vomiting in Patients With Advanced Cancer
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ClinicalTrials.gov Identifier: NCT00124930
(Study suspended due to low enrollment)
The purpose of this study is to compare the efficacy and safety of Haldol (haloperidol) and olanzapine in the control of chronic nausea with advanced cancer patients who have failed first line antiemetic therapy.
Condition or disease
Drug: OlanzapineDrug: Haldol
The purpose of this study is to compare the efficacy and safety of haloperidol and olanzapine in the control of chronic nausea with advanced cancer patients who have failed first line antiemetic therapy.
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Ages Eligible for Study:
18 Years and older (Adult, Senior)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
>18 years of age
Failed maxeran and domperidone
Underlying treatment of causes has failed
Adequate cognitive function
Partial/complete bowel obstruction
Currently taking Haldol or olanzapine
Has drug induced extrapyramidal symptoms
Undergoing chemotherapy or radiotherapy (RT) to brain, abdomen, stomach or esophagus