Peripartum Bacteruria and Urinary Tract Infections (UTI)
Recruitment status was Recruiting
In the last years urinary tract infections (UTI) and pyelonephritis have been the most common reason for readmission to our hospital after birth. UTI is know to be one of the leading causes of postpartum fever affecting about 3%-8% of all postpartum women.
The investigators hypothesize that collecting urine cultures pre- and postnatally may help identify women at risk for developing UTI, while treating women with positive cultures could decrease the rehospitalization rate due to postpartum fever. Collecting data during delivery may help identify women at risk for this complication.
Urinary Tract Infection
Procedure: urine culture
Drug: antibiotics according to culture
|Study Design:||Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Prevention
|Official Title:||Risk Factors for Postpartum Bacteruria, Does Labor Cause UTI?|
- Rate of rehospitalization for postpartum fever
- Incidence of UTI in the early puerperium
|Study Start Date:||January 2004|
|Estimated Study Completion Date:||June 2005|
The study is planned as a randomized controlled study with 500 women in each arm. The study group will have pre and post labor urine cultures taken, and the risk factors during delivery will be documented, while the control group will have no cultures taken, as the common practice prior to the study.
Women with positive cultures will be contacted by telephone, and antibiotic treatment recommended according to bacteria sensitivity. All women will be contacted by telephone 1 month post partum and data regarding urinary tract symptoms and need for hospitalization, will be collected. The rehospitalization rate will be documented and compared between the two groups.
The assumption is that routine urine culture to women in the peripartum period may reduce the UTI rate and hospitalization after delivery.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00121797
|Contact: Arik Tzukert, DMD||00 972 2 firstname.lastname@example.org|
|Contact: Hadas Lemberg, PhD||00 972 2 email@example.com|
|Clinical microbiology, Hadassah Ein-Kerem Medical centre||Recruiting|
|Contact: Mervin Shapiro, MD 00 972 2 6777111|
|Principal Investigator: Mervin Shapiro, MD|
|Obs&Gyn Hadassah Ein-Kerem Medical center||Recruiting|
|Contact: David Mankuta, MD 00 972 2 6776425 firstname.lastname@example.org|
|Sub-Investigator: David Mankuta, MD|
|Principal Investigator:||Tamar Elram, MD||Hadassah Medical Organization|