Mean Arterial Pressure (MAP) and Renal Perfusion: Evaluation of Critically Ill Patients With Normal Creatinine or Reduced Renal Function

This study has suspended participant recruitment.
Information provided by:
University Hospital, Ghent Identifier:
First received: June 30, 2005
Last updated: December 19, 2007
Last verified: December 2007
The purpose of this study is to evaluate the renal perfusion depending on the MAP.

Condition Intervention
Kidney Failure, Acute
Procedure: controlling the MAP

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Crossover Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: MAP and Renal Perfusion: Evaluation of Critically Ill Patients With Normal Creatinine or Reduced Renal Function

Resource links provided by NLM:

Further study details as provided by University Hospital, Ghent:

Primary Outcome Measures:
  • creatinine clearance after 4 hours

Secondary Outcome Measures:
  • resistance index
  • diuresis
  • urinary indices of renal function

Estimated Enrollment: 60
Study Start Date: February 2003

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Over 18 years old
  • Intensive care patient
  • Treated with vasopressor
  • Given informed consent
  • Arterial infusion
  • A bladder catheter

Exclusion Criteria:

  • Anamneses of hypertension
  • Neurological trauma
  • Acute renal insufficiency other than prerenal or acute tubular necrosis etiology
  • Hepatorenal syndrome
  • Treated with diuretics
  • Mechanical ventilation and unstable
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00117416

University Hospital Ghent
Ghent, Belgium, 9000
Sponsors and Collaborators
University Hospital, Ghent
Principal Investigator: Eric Hoste, MD, PhD University Hospital, Ghent
  More Information

Additional Information:
No publications provided Identifier: NCT00117416     History of Changes
Other Study ID Numbers: 2002/382
Study First Received: June 30, 2005
Last Updated: December 19, 2007
Health Authority: Belgium: Federal Agency for Medicines and Health Products, FAMHP

Additional relevant MeSH terms:
Acute Kidney Injury
Critical Illness
Renal Insufficiency
Disease Attributes
Kidney Diseases
Pathologic Processes
Urologic Diseases processed this record on November 25, 2015