Magnesium Sulfate Versus Indomethacin for Preterm Labor
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ClinicalTrials.gov Identifier: NCT00116623
Recruitment Status :
The purpose of this study is to investigate the efficacy of Indomethacin compared to Magnesium Sulfate (MgSO4) in reducing neonatal morbidity through a prospective double blind randomized clinical trial. The specific aim of the project is to test the hypothesis that Indomethacin, compared to MgSO4, will decrease the proportion of neonates diagnosed with major complications or death.
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Ages Eligible for Study:
Child, Adult, Senior
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Initial episode of preterm labor for enrollment
The diagnosis of preterm labor
Gestational age between 24 and 32 weeks
Singleton or twin gestation
The ability to understand the requirements of the study
Cervical dilation >5 cms
History of gastrointestinal bleeding
Abnormal renal function
Suspicion of fetal malformation by ultrasound
Known allergy to, or intolerance of, Magnesium sulfate and/or Indomethacin