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Functional Circuit Training in Older Adults With Congestive Heart Failure

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00108147
First Posted: April 15, 2005
Last Update Posted: March 6, 2009
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
VA Office of Research and Development
  Purpose
The goal of this study is to determine the effect of a functional circuit training program as compared to standard cardiac rehabilitation or control exercise in improving physical function and activity.

Condition Intervention
Heart Failure, Congestive Procedure: Circuit Training Procedure: Cardiac Rehabilitation Procedure: Flexibility and toning

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single
Official Title: Functional Circuit Training in Older Adults With Congestive Heart Failure

Resource links provided by NLM:


Further study details as provided by VA Office of Research and Development:

Study Start Date: October 2003
Arms Assigned Interventions
Experimental: 1
Circuit Training
Procedure: Circuit Training
Active Comparator: 2
Cardiac Rehabilitation
Procedure: Cardiac Rehabilitation
Active Comparator: 3
Flexibility and toning
Procedure: Flexibility and toning

Detailed Description:

In older (65 years of age or older) patients with congestive heart failure, we propose to:

  1. Assess: a) Peak aerobic capacity (peak VO2) during a monitored, standardized treadmill test; b) Oxygen uptake kinetics and heart rate during a standardized submaximal treadmill test; c) Performance on a set of functional mobility tasks; d) Self-report of physical disability and difficulty in performing daily tasks, and physical activity.
  2. Conduct a 12-week randomized controlled trial, comparing changes in these assessed measures in patients randomized to three different groups: 1) standard cardiac rehabilitation using bicycle exercise; 2) group functional circuit training focusing on exercises that involve functional mobility tasks and a home-activities exercise component; 3) a chair-based, flexibility and "toning " (low level resistance) group control exercise.
  3. Reassess all groups after an additional 12 weeks in the measures identified above to identify how well the three groups maintain their function.
  4. Examine the mechanisms underlying change in functional mobility performance and self-reported function as a result of the interventions

Primary hypothesis 1: Compared to chair-based exercise controls at the end of week 12, both the cardiac rehabilitation and functional circuit training groups will show improvements in measures of peak aerobic capacity, submaximal oxygen uptake kinetics, functional mobility performance, and self-reported function.

Primary hypothesis 2: Compared to the other two groups that are given exercise instructions only, the functional circuit training group, who continue their home activities exercise program, show less decline by week 24 in measures of peak aerobic capacity, submaximal oxygen uptake kinetics, functional mobility performance, and self-reported function.

Secondary hypothesis: Measures of submaximal oxygen uptake kinetics are better predictors of changes in functional mobility performance and self-reported function than peak aerobic capacity, muscle strength, joint range of motion, balance, and behavioral factors (such as depression).

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   60 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Congestive Heart Failure

Exclusion Criteria:

  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00108147


Locations
United States, Michigan
VA Ann Arbor Healthcare System
Ann Arbor, Michigan, United States, 48113
Sponsors and Collaborators
VA Office of Research and Development
Investigators
Principal Investigator: Neil Alexander, MD VA Ann Arbor Healthcare System
  More Information

Responsible Party: Alexander, Neil - Principal Investigator, Department of Veterans Affairs
ClinicalTrials.gov Identifier: NCT00108147     History of Changes
Other Study ID Numbers: AGCG-002-03S
First Submitted: April 14, 2005
First Posted: April 15, 2005
Last Update Posted: March 6, 2009
Last Verified: March 2009

Keywords provided by VA Office of Research and Development:
Aged
Congestive Heart Failure
Exercise

Additional relevant MeSH terms:
Heart Failure
Heart Diseases
Cardiovascular Diseases