Consortium On Risk for Early-onset Parkinson's Disease (CORE PD)
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00104585|
Recruitment Status : Unknown
Verified January 2012 by Columbia University.
Recruitment status was: Recruiting
First Posted : March 2, 2005
Last Update Posted : January 19, 2012
|Condition or disease|
Parkinson's disease (PD) is a common, neurodegenerative condition. Although mostly a late-onset disorder, 10 percent of people with PD are reported to develop symptoms before the age of 50. To date, six genes have been found to be associated with PD, however the majority have been found in rare PD 'families'. Some studies have also identified a number of environmental risk factors, such as pesticide use, that appear to increase the risk of PD.
In a previous study, Dr. Karen Marder and her research team found that close family members of people with both early- and late-onset PD have a three-fold increased risk of PD compared to close family members of people without PD.
The purpose of the Consortium On Risk for Early-onset Parkinson's Disease (CORE PD) study is to identify the genetic factors that contribute to the development of early-onset Parkinson's disease, and to understand how these genetic factors interact with other genes and the environment to cause PD.
Participation in the study involves a blood draw (to look for genetic factors associated with PD), questionnaires collecting information on family and medical history, and a neurological examination. In addition participants may be contacted in the future and asked to participate in a more detailed interview. At that time, study investigators will also ask participants for permission to contact family members to invite them to participate in the study.
This research study requires participants to sign a consent form, which states that the research is voluntary and confidential. In addition, since this is a research study, genetic results are not released to participants or their family members now or in the future.
Scientists hope this multi-center study will increase the current knowledge of PD and that the identification of factors that cause PD will lead to better diagnosis and treatment.
|Study Type :||Observational|
|Estimated Enrollment :||800 participants|
|Official Title:||Genetic Epidemiology of Parkinson's Disease|
|Study Start Date :||July 2004|
|Estimated Primary Completion Date :||September 2012|
People with young onset Parkinson's disease and their family members
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00104585
|Contact: Helen Mejia-Santana, M.A.||firstname.lastname@example.org|
|United States, California|
|The Parkinson's Institute||Active, not recruiting|
|Sunnyvale, California, United States, 94089|
|United States, Connecticut|
|The Institute for Neurodegenerative Disorders||Active, not recruiting|
|New Haven, Connecticut, United States, 06510|
|United States, Illinois|
|Rush University Medical Center||Recruiting|
|Chicago, Illinois, United States, 60612|
|Contact: Lucia M. Blasucci 312-563-2900 Lucia_M_Blasucci@rush.edu|
|Glenbrook Hospital, Evanston||Active, not recruiting|
|Glenview, Illinois, United States, 60026|
|United States, Maryland|
|Johns Hopkins Hospital||Active, not recruiting|
|Baltimore, Maryland, United States, 21287|
|United States, Minnesota|
|Struthers Parkinson's Center||Active, not recruiting|
|Golden Valley, Minnesota, United States, 55427|
|United States, New York|
|Beth Israel Medical Center||Active, not recruiting|
|New York, New York, United States, 10003|
|New York, New York, United States, 10032|
|Contact: Helen Mejia-Santana 877-305-2438 email@example.com|
|United States, Pennsylvania|
|University of Pennsylvania||Active, not recruiting|
|Philadelphia, Pennsylvania, United States, 19104|
|United States, Rhode Island|
|Neuro Health||Active, not recruiting|
|Warwick, Rhode Island, United States, 02886|
|United States, Tennessee|
|University of Tennessee Health Science Center||Active, not recruiting|
|Memphis, Tennessee, United States, 38136|
|United States, Wisconsin|
|Marshfield Clinic||Active, not recruiting|
|Marshfield, Wisconsin, United States, 54449|
|Principal Investigator:||Karen Marder, M.D., M.PH.||Columbia University|