A Study of MK0731 in Patients With Advanced Solid Tumors (0731-002)(COMPLETED)
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|ClinicalTrials.gov Identifier: NCT00104364|
Recruitment Status : Completed
First Posted : February 28, 2005
Last Update Posted : January 30, 2015
The purpose of this trial is to study MK0731 in patients with recurrent or non-responsive solid tumors, or cancers for which standard therapy does not exist.
This is an early phase trial and some specific protocol information is proprietary and not publicly available at this time. (Full information is available to trial participants).
|Condition or disease||Intervention/treatment||Phase|
|Cancer||Drug: MK0731||Phase 1|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||30 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||An Open-label, Dose Escalation Phase I/II Trial of a KSP Inhibitor Given as a Constant 24-Hour Infusion in Patients With Advanced Solid Tumors|
|Study Start Date :||May 2005|
|Actual Primary Completion Date :||January 2008|
|Actual Study Completion Date :||January 2008|
- Safety and tolerability of MK0731 administered as a 24-hour CIV Infusion. Dose limiting toxicities. Maximum tolerated dose and recommended Phase II dose of L-001154704 administered as a 24 hour CIV infusion.
- Predose predictive biomarkers of response to MK0731
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00104364
|Study Director:||Medical Monitor||Merck Sharp & Dohme Corp.|