Osteoarthritis: Weakness From Inflammation
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00104312|
Recruitment Status : Completed
First Posted : February 25, 2005
Last Update Posted : May 29, 2009
|Condition or disease|
Through this study, we hope to learn about the natural history of knee osteoarthritis and the disability that arises from it. We hope to better understand why people with knee osteoarthritis develop difficulty with mobility (e.g. walking, standing) in hopes of finding a cure.
This study requires 1 four-hour visit to Harbor Hospital. The visit involves a physical exam, a DEXA bone density scan, blood and urine testing, knee x-rays, strength testing and a surface electromyography (EMG). Samples of muscle, joint fluid and joint tissue will be collected during your planned surgery.
Participation in this study is entirely voluntary.
|Study Type :||Observational|
|Estimated Enrollment :||88 participants|
|Official Title:||Weakness From Inflammation: A Basis of Disability From Knee Osteoarthritis|
|Study Start Date :||April 2001|
|Actual Primary Completion Date :||May 2009|
|Actual Study Completion Date :||May 2009|
Participants with symptomatic knee osteoarthritis
Participants without symptomatic knee osteoarthritis, age-matched as controls
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00104312
|United States, Maryland|
|Baltimore, Maryland, United States, 21225|
|Principal Investigator:||Shari Ling, MD||NIA, Johns Hopkins Medical Institution Divisions of Rheumatology, Gerontology, and Geriatrics|