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Qigong Therapy for Individuals With Knee Osteoarthritis

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ClinicalTrials.gov Identifier: NCT00104156
Recruitment Status : Completed
First Posted : February 24, 2005
Last Update Posted : January 25, 2008
Information provided by:

Study Description
Brief Summary:

The purpose of this study is to evaluate the effectiveness of Qigong therapy, an ancient Chinese practice, for pain relief and symptom improvement in people with knee osteoarthritis (OA).

Study hypotheses: 1) Qigong therapy will result in greater reduction of pain and greater symptom improvement than sham treatment. 2) Individuals with a history of complementary and alternative medicine (CAM) use will be more likely to experience benefits of Qigong therapy than those without such experience.

Condition or disease Intervention/treatment Phase
Osteoarthritis Procedure: External Qigong therapy Phase 2

Detailed Description:

OA is the leading cause of disability in the United States. Standard treatment for OA is drug therapy; however, cost, side effects, and varying levels of effectiveness warrant the need for development of new treatments. Qigong therapy, which involves deep meditation, breathing exercises, and the harnessing of energy, may be an effective treatment for OA.

According to traditional Chinese medicine, Qi (Chi) is the "life force" that flows through the body and keeps people healthy and vital. In the practice of traditional Chinese medicine, arthritis is thought to be due to a blockage of the flow of Qi or a buildup of abnormal or damaging Qi. It is believed that releasing this buildup or breaking the blockage of Qi through Qigong therapy may relieve OA symptoms.

Participants will be randomly assigned to receive five sessions of either Qigong therapy or sham treatment over a period of 2 weeks. During Qigong therapy, a therapist will send his or her Qi to the arthritic knees through touch and meditation. Similar body work will be performed during the sham treatment, but no Qi will be harnessed. Self-report scales that measure pain, stiffness, anxiety, daily drug use, CAM use, and overall functioning will be used to assess participants. The assessments will occur at study start and at a 3-month follow-up visit.

Study Design

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 100 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double
Primary Purpose: Treatment
Official Title: Qigong Therapy for Osteoarthritis at Knees
Study Start Date : January 2005
Primary Completion Date : August 2007
Study Completion Date : August 2007

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Osteoarthritis
U.S. FDA Resources

Arms and Interventions

Outcome Measures

Primary Outcome Measures :
  1. Pain, stiffness, and physical function scale results

Secondary Outcome Measures :
  1. McGill Pain Questionnaire (MPQ-SF) results
  2. Spielberger State-Trait Anxiety Scale (STAI) results
  3. Daily dosage of drugs for pain relief
  4. Range of motion for knees
  5. Time to walk 50 feet

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Diagnosis of osteoarthritis at least 6 months prior to study entry
  • Able to understand English

Exclusion Criteria:

  • Inflammatory joint disease affecting leg movement
  • Knee replacement surgery on the OA knee
  • Depo-corticosteroid knee injections within 3 months prior to study entry
  • Pain in hips or lower back affecting leg movement
  • New arthritis drugs or other painkillers within 2 weeks prior to study entry
  • Investigational drugs within 30 days prior to study entry
  • Asthma requiring oral corticosteroids within 4 weeks prior to study entry
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00104156

United States, New Jersey
University of Medicine and Dentistry, New Jersey-Robert Wood Johnson Medical School
Newark, New Jersey, United States, 07103
University of Medicine and Dentistry, New Jersey-Robert Wood Johnson Medical School
Piscataway, New Jersey, United States, 08854
Sponsors and Collaborators
National Center for Complementary and Integrative Health (NCCIH)
Principal Investigator: Kevin W. Chen, PhD MPH Division of Addiction Psychiatry, University of Medicine and Dentistry, New Jersey-Robert Wood Johnson Medical School
Principal Investigator: Leonard Sigal, MD Rheumatology Department - Biomedical Sciences Program, University of Medicine and Dentistry, New Jersey-Robert Wood Johnson Medical School
More Information

ClinicalTrials.gov Identifier: NCT00104156     History of Changes
Other Study ID Numbers: R21AT001352-01A2 ( U.S. NIH Grant/Contract )
First Posted: February 24, 2005    Key Record Dates
Last Update Posted: January 25, 2008
Last Verified: January 2008

Keywords provided by National Center for Complementary and Integrative Health (NCCIH):
Knee pain
Breathing Exercises

Additional relevant MeSH terms:
Joint Diseases
Musculoskeletal Diseases
Rheumatic Diseases