Efficacy and Safety of Zoledronic Acid in the Prevention and Treatment of Corticosteroid Induced Osteoporosis
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The intake of high doses of corticosteroids is known to play an important role in the weakening of the bones and is thus an increasing fracture risk. Zoledronic acid (Aclasta) is a drug known for its protective effect in some bone diseases (tumors, paget). This study will test the safety and efficacy of zoledronic acid in the prevention and treatment of corticosteroid induced osteoporosis in male and female patients.
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Ages Eligible for Study:
18 Years to 85 Years (Adult, Senior)
Sexes Eligible for Study:
Long duration treatment with corticosteroids (started or ongoing)
History of osteogenesis imperfecta, multiple myeloma or Paget's disease
History of Hyperparathyroidism, hyperthyroidism
History of Osteomalacia
Other protocol-defined inclusion/exclusion criteria may apply.