CALERIE (PBRC, Baton Rouge) - Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy
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|ClinicalTrials.gov Identifier: NCT00099151|
Recruitment Status : Completed
First Posted : December 9, 2004
Last Update Posted : December 11, 2009
|Condition or disease||Intervention/treatment||Phase|
|Aging Cardiovascular Disease Diabetes Mellitus||Behavioral: Caloric Restriction (CR) Behavioral: Exercise||Not Applicable|
This study tests whether chronic caloric restriction improves risk factors of longevity in humans as it is known to do in animals, by measuring a variety of factors dealing with metabolism and oxidative stress, through physical evaluations and laboratory tests.
Participants will receive dietary counseling and free medical evaluations. In addition, each volunteer will be asked to do one of the following:
- Follow a reduced calorie diet
- Follow a reduced calorie diet using a liquid diet
- Increase physical activity while on a reduced calorie diet
- Follow a standard diet.
Three separate five-day inpatient stays are required.
|Study Type :||Interventional (Clinical Trial)|
|Enrollment :||48 participants|
|Intervention Model:||Parallel Assignment|
|Official Title:||Metabolic Adaptations to Six Month Caloric Restriction|
|Study Start Date :||March 2002|
|Actual Primary Completion Date :||May 2006|
|Actual Study Completion Date :||May 2006|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00099151
|United States, Louisiana|
|Pennington Biomedical Research Center, 6400 Perkins Road|
|Baton Rouge, Louisiana, United States, 70808|
|Principal Investigator:||Eric Ravussin, Ph.D.||Pennington Biomedical Research Center|
|Principal Investigator:||Donald Williamson, Ph.D.||Pennington Biomedical Research Center|