Identification of the Cranberry Juice Compounds That Prevent Urinary Tract Infections
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00087828|
Recruitment Status : Completed
First Posted : July 16, 2004
Last Update Posted : August 18, 2006
|Condition or disease||Intervention/treatment||Phase|
|Urinary Tract Infections||Drug: Cranberry juice cocktail||Not Applicable|
Urinary tract infections (UTIs) are a significant health issue, with one fourth of all women experiencing symptoms during their lifetimes. Cranberry juice has been shown to reduce the incidence of UTIs by preventing bacteria from adhering to the bladder. However, the compounds that direct this activity have not been identified. This study will identify and examine UTI-reducing compounds in cranberry juice.
Participants in this study will drink a specified amount of water following an overnight fast. Their urine will be collected 1 to 3 hours after the water is consumed. Several days later, the women will be provided with cranberry juice to replace the water in the regimen. Urine samples will be analyzed for compounds that have antibacterial or antiadhesion activity against the bacteria that cause UTIs.
|Study Type :||Interventional (Clinical Trial)|
|Enrollment :||5 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Cranberry Juice Metabolites in Urine|
|Study Start Date :||November 2000|
|Study Completion Date :||June 2005|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00087828
|United States, Illinois|
|Dept Medicinal Chemistry & Pharmacognosy, COP, UIC|
|Chicago, Illinois, United States, 60612|
|Principal Investigator:||Susan Turner, MD||UIC|