Racial Difference in HCV/Host Interactions
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00071916|
Recruitment Status : Unknown
Verified March 2010 by National Institute of Allergy and Infectious Diseases (NIAID).
Recruitment status was: Recruiting
First Posted : November 5, 2003
Last Update Posted : October 29, 2010
|Condition or disease|
|Study Type :||Observational|
|Estimated Enrollment :||260 participants|
|Observational Model:||Case Control|
|Official Title:||African American Response to Therapy for Hepatitis C|
|Study Start Date :||March 2001|
|Estimated Study Completion Date :||June 2010|
Adult African American participants with compensated chronic hepatitis C who have not been previously been treated with interferon and/or ribavirin.
Caucasian participants with compensated chronic hepatitis C who have not been previously been treated with interferon and/or ribavirin.
- Determine if there is a difference in interferon-induced signaling between patients that respond to therapy and those that do not. [ Time Frame: Analysis. ]
- Measure and compare the sustained virologic response to standard treatment for hepatitis C between African American (AA) and non AA patients. [ Time Frame: Analysis. ]
- Determine how human leukocyte antigen (HLA) class II-dependent immune regulation and T cell specificities affect differences in immune responses to hepatitis C (HCV) and response to therapy in African American (AA) patients compared to non AA patients. [ Time Frame: Analysis. ]
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00071916
|Contact: Jaquelyn Fleckenstein||(901) firstname.lastname@example.org|
|United States, Arkansas|
|University of Arkansas||Recruiting|
|Little Rock, Arkansas, United States, 72205|
|United States, Tennessee|
|University of Tennessee||Recruiting|
|Memphis, Tennessee, United States, 38163|
|Contact: Jaquelyn Fleckenstein|
|Nashville, Tennessee, United States, 37232|