A Study Evaluating Topical Recombinant Human Vascular Endothelial Growth Factor (Telbermin) for Induction of Healing of Chronic, Diabetic Foot Ulcers
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|ClinicalTrials.gov Identifier: NCT00069446|
Recruitment Status : Completed
First Posted : September 26, 2003
Last Update Posted : May 11, 2017
|Condition or disease||Intervention/treatment||Phase|
|Foot Ulcer||Drug: rhuMAb VEGF (telbermin)||Phase 1|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||50 participants|
|Official Title:||An Exploratory, Double-Blind, Randomized, Placebo Controlled Study Evaluating Topical Recombinant Human Vascular Endothelial Growth Factor (Telbermin) for Induction of Healing of Chronic, Diabetic Foot Ulcers|
|Actual Study Start Date :||August 2003|
|Primary Completion Date :||October 2004|
|Study Completion Date :||October 2004|
- Incidence of clinically significant hypotension.
- Incidence of clinically significant ulcer infection defined by increased discharge and malodorous exudates from the ulcer, fever, and a white blood cell (WBC) count of >10,000/uL
- Development of anti telbermin antibodies
- Incidence of adverse events
- Percent reduction in total ulcer surface area.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00069446
|Study Director:||Tim Breen, Ph.D.||Genentech, Inc.|