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Physical Activity and Childhood Obesity

This study has been withdrawn prior to enrollment.
(CI left institution)
Sponsor:
ClinicalTrials.gov Identifier:
NCT00063544
First Posted: July 1, 2003
Last Update Posted: May 26, 2016
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Collaborator:
National Heart, Lung, and Blood Institute (NHLBI)
Information provided by (Responsible Party):
Anna Brooke, University of Bristol
  Purpose
To measure associations between physical activity and obesity in a large, population-based cohort of children.

Condition
Cardiovascular Diseases Heart Diseases Obesity

Study Type: Observational
Official Title: Physical Activity and Childhood Obesity

Resource links provided by NLM:


Further study details as provided by Anna Brooke, University of Bristol:

Primary Outcome Measures:
  • Levels and patterns of physical activity will be measured on all children at ages 11 and 13 to assess relationships with measures of obesity. [ Time Frame: 5 days ]
    In this study, physical activity will be measured using a single-plane accelerometer (CSA model 7164) - a small, lightweight electronic motion sensor attached to the child's belt for a period of 5 days. This instrument gives the capacity to to characterize children's physical activity, and inactivity, more accurately than ever before.


Enrollment: 0
Study Start Date: May 2003
Study Completion Date: April 2007
Primary Completion Date: April 2007 (Final data collection date for primary outcome measure)
Detailed Description:

BACKGROUND:

Childhood obesity is rapidly increasing in many countries and environmental factors are the main cause. The onset of puberty may be a critical period. Diet and physical activity are likely to be prime causative factors, although the relative role of each may vary between children of differing age, gender and ethnicity. There are also likely to be many psychosocial and social-demographic factors that can confound these relationships, and these confounders may vary between sub-groups. There continues to be uncertainty regarding the role of these factors and their differential effects in subgroups of the population. It is crucial to develop a better understanding of how dietary and physical activity patterns affect energy balance, and how these characteristics interact with other factors.

Measures of physical activity will be added to ongoing assessments of boys and girls (n=10,000) participating in the Avon Longitudinal Study of Parents and Children (ALSPAC). This comprehensive study has been following children and their parents for about 9-10 years. The study has an extensive database including maternal and paternal social background, lifestyle and habits (including diet and physical activity), medical history and medications during pregnancy and thereafter. ALSPAC has also collected and retained biological samples including maternal blood, urine, cord blood, umbilical cord, placenta, hair and nail clippings, deciduous teeth, child's blood and DNA. Data on the mothers also include details of her own parent's lifestyle, her childhood, lifestyle, occupation history and diet, and access to mother's biological samples. Over 71% of the cohort (>10,000 of 14,541 participants) have been retained.

DESIGN NARRATIVE:

Levels and patterns of physical activity will be measured on all children at ages 11 and 13 to assess relationships with measures of obesity. Physical activity will be measured objectively for 5 days. The data, together with other data collected during pregnancy, infancy and childhood will be used to investigate relationships between modes, intensities, quantities and patterns of physical activity and the development of obesity at this critical stage of life. The strengths of this prospective study are its size, high retention rates and the extensive set of whole-of-life measures already taken on the children. With over 10,000 children expected to attend annually for health checks throughout adolescence, the study will be adequately powered to quantify associations between physical activity and obesity. The study of physical activity in children has to date been seriously restricted because of high levels of measurement error inherent in all self-report measures of physical activity. In this study, physical activity will be measured using a single-plane accelerometer (CSA model 7164) - a small, lightweight electronic motion sensor attached to the child's belt for a period of 5 days. This instrument gives the capacity to to characterize children's physical activity, and inactivity, more accurately than ever before. Comprehensive measurements of diet and body composition (principally Dual-emission X-ray Absorptiometry - DXA) will also be taken at ages 11 and 13 under separate funding.

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   11 Years to 13 Years   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Not an applicable clinical trial
Criteria
No eligibility criteria - Not an applicable clinical trial
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00063544


Sponsors and Collaborators
Anna Brooke
National Heart, Lung, and Blood Institute (NHLBI)
Investigators
Principal Investigator: Chris Riddoch Bristol University
  More Information

Responsible Party: Anna Brooke, Research Governance Officer, University of Bristol
ClinicalTrials.gov Identifier: NCT00063544     History of Changes
Other Study ID Numbers: 1219
R01HL071248 ( U.S. NIH Grant/Contract )
First Submitted: June 30, 2003
First Posted: July 1, 2003
Last Update Posted: May 26, 2016
Last Verified: May 2016

Additional relevant MeSH terms:
Obesity
Cardiovascular Diseases
Heart Diseases
Pediatric Obesity
Overnutrition
Nutrition Disorders
Overweight
Body Weight
Signs and Symptoms