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Trial record 14 of 178 for:    "Mitochondrial Diseases" OR "mitochondrial neurogastrointestinal encephalopathy disease"

RG2133 (2',3',5'-Tri-O-Acetyluridine) in Mitochondrial Disease

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ClinicalTrials.gov Identifier: NCT00060515
Recruitment Status : Terminated
First Posted : May 8, 2003
Last Update Posted : August 5, 2005
Sponsor:
Information provided by:
Repligen Corporation

Brief Summary:
The objective of the study is to determine the safety and tolerability of RG2133 in patients with Mitochondrial Disease.

Condition or disease Intervention/treatment Phase
Mitochondrial Diseases Drug: RG2133 (2',3',5'-tri-O-acetyluridine) Phase 1

Study Type : Interventional  (Clinical Trial)
Enrollment : 12 participants
Allocation: Non-Randomized
Primary Purpose: Treatment
Official Title: An Open-Label Dose-Escalation Phase I Study to Asses the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RG2133 (2',3',5'-Tri-O-Acetyluridine) in the Treatment of Inherited Mitochondrial Diseases






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Ages Eligible for Study:   3 Years and older   (Child, Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria
Mitochondrial Disease

ClinicalTrials.gov Identifier: NCT00060515     History of Changes
Other Study ID Numbers: RG2133-01
First Posted: May 8, 2003    Key Record Dates
Last Update Posted: August 5, 2005
Last Verified: August 2005

Additional relevant MeSH terms:
Mitochondrial Diseases
Metabolic Diseases