Familial Aggregation of Barrett's Esophagus
The recruitment status of this study is unknown because the information has not been verified recently.
Verified March 2010 by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
Recruitment status was Active, not recruiting
Information provided by:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
First received: April 14, 2003
Last updated: March 17, 2010
Last verified: March 2010
This research study is trying to determine whether Barrett's esophagus and associated esophageal cancers, specifically esophageal adenocarcinoma are inherited in certain families. Persons who are affected with Barrett's esophagus or esophageal cancer (adenocarcinoma type) are asked to complete a questionnaire that determines their habits and asks a detailed family history. Family members of patients seen at University Hospitals of Cleveland are also being recruited for screening tests of their esophagus. The investigators plan to eventually screen family members at all participating institutions. This research will eventually lead to the identification of inherited genetic changes that cause Barrett's esophagus and esophageal cancer. It will help the investigators develop better methods for preventing or identifying esophageal cancer at an early curable stage.
||Familial Aggregation of Barrett's Esophagus
| Estimated Enrollment:
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
Eligible cases will be defined as those patients and their family members who meet the following criteria:
- Barrett's esophagus confirmed by review of pathology and endoscopy report or adenocarcinoma of the esophagus or family members of person with Barrett's esophagus or adenocarcinoma of the esophagus.
- Male or female age 18 or older at time of enrollment or male or female less than 18 years of age at time of enrollment with parental consent.
- Ability to give informed consent, if patient is age 18 or older.
- No history of radiation to the chest or abdomen.
- No history of chemotherapy in the year preceding the initial diagnosis of Barrett's esophagus or esophageal adenocarcinoma.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study.
To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.
For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00058877
|Cleveland Clinic Foundation
|Cleveland, Ohio, United States |
|University Hospitals of Cleveland
|Cleveland, Ohio, United States, 44106-8066 |
|Ohio State University
|Columbus, Ohio, United States |
|Vanderbilt University Medical Center
|Nashville, Tennessee, United States |
No publications provided
History of Changes
|Other Study ID Numbers:
|Study First Received:
||April 14, 2003
||March 17, 2010
||United States: Federal Government
Keywords provided by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK):
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on April 23, 2015
Digestive System Abnormalities
Digestive System Diseases
Digestive System Neoplasms
Head and Neck Neoplasms
Neoplasms by Site