Magnetic Resonance Imaging in Women Recently Diagnosed With Unilateral Breast Cancer
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|ClinicalTrials.gov Identifier: NCT00058058|
Recruitment Status : Completed
First Posted : April 9, 2003
Last Update Posted : October 24, 2012
RATIONALE: Diagnostic procedures such as magnetic resonance imaging (MRI) may improve the ability to detect cancer in the unaffected breast of women recently diagnosed with unilateral breast cancer.
PURPOSE: Diagnostic trial to determine the effectiveness of MRI in evaluating the unaffected breast of women recently diagnosed with unilateral breast cancer.
|Condition or disease||Intervention/treatment||Phase|
|Breast Cancer||Procedure: magnetic resonance imaging Radiation: gadopentetate dimeglumine||Not Applicable|
- Determine the diagnostic yield of magnetic resonance imaging (MRI) in evaluating the contralateral breast of women with a recent unilateral diagnosis of breast cancer and a negative contralateral mammogram and clinical breast exam.
- Determine the sensitivity, specificity, positive predictive value for both call backs for additional imaging and biopsy recommendations, and receiver operating characteristic curves of MRI in evaluating these patients.
- Determine the effect of the following patient-related factors: age (50 years old and over vs less than 50 years old), breast parenchymal density (fatty vs non fatty breast), and tumor histology (invasive lobular vs invasive ductal, invasive vs in situ) on the performance of MRI (cancer yield, sensitivity, specificity, and PPV).
OUTLINE: This is a multicenter study.
Patients receive gadopentetate dimeglumine IV and then undergo magnetic resonance imaging of the contralateral breast.
Patients are followed at 12-18 and 24-30 months.
PROJECTED ACCRUAL: A total of 1,000 patients will be accrued for this study.
|Study Type :||Interventional (Clinical Trial)|
|Official Title:||MRI Evaluation Of The Contralateral Breast In Women With Recent Diagnosis Of Breast Cancer|
|Study Start Date :||February 2001|
|Actual Primary Completion Date :||March 2007|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00058058
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|Study Chair:||Constance Lehman, MD, PhD||Seattle Cancer Care Alliance|