Trial record 72 of 3555 for:    Louisville | ( Map: United States )

Treatment of Depression in Nursing Homes

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00056485
Recruitment Status : Completed
First Posted : March 17, 2003
Last Update Posted : April 13, 2017
National Institute of Mental Health (NIMH)
Information provided by (Responsible Party):
Suzanne Meeks, University of Louisville

Brief Summary:
This study will implement a treatment for depression in a nursing home setting.

Condition or disease Intervention/treatment Phase
Depression Behavioral: Pleasant Events-Based Behavioral Intervention Not Applicable

Detailed Description:

Depression in long-term care facilities is a significant public health issue. Up to 50% of nursing home residents are affected by significant depressive symptoms. The decreased health and limited cognitive ability of many nursing home residents makes treatment and research extremely challenging. This study will attempt to identify and implement treatments for depressed nursing home residents.

Participants are randomly assigned to receive either an active intervention or treatment as usual for 6 weeks. The active intervention is followed by 4 weeks of maintenance. The intervention is implemented primarily by existing nursing facility staff and focuses on increasing opportunities for residents to experience pleasant events through increased levels of activity and positive affect. The maintenance treatment involves incorporation of protocol-based activities into patient care plans. Patients have a follow-up visit 12 weeks after the study. Psychiatric evaluations, depression and mood rating scales, observed affect and activity participation, behavior problems, and staff burden are assessed.

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 25 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Intervention Model Description: This was a pilot feasibility study; the first part was a single group; the second part was a two-group randomized design.
Masking: None (Open Label)
Primary Purpose: Other
Official Title: Behavioral Intervention for Depression in Nursing Homes
Study Start Date : April 2002
Actual Primary Completion Date : August 2006
Actual Study Completion Date : August 2006

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Nursing Homes

Information from the National Library of Medicine

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Ages Eligible for Study:   60 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Nursing home residents
  • DSM-IV criteria for major depressive disorder or dysthymia or Research Diagnostic Criteria for minor depressive disorder with current Geriatric Depression Scale scores > 11 and Mini Mental State scores >= 14

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00056485

United States, Kentucky
University of Louisville
Louisville, Kentucky, United States, 40292
Sponsors and Collaborators
University of Louisville
National Institute of Mental Health (NIMH)
Principal Investigator: Suzanne Meeks, PhD University of Louisville

Responsible Party: Suzanne Meeks, Professor, University of Louisville Identifier: NCT00056485     History of Changes
Other Study ID Numbers: R21MH063073 ( U.S. NIH Grant/Contract )
R21MH063073 ( U.S. NIH Grant/Contract )
First Posted: March 17, 2003    Key Record Dates
Last Update Posted: April 13, 2017
Last Verified: April 2017
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No

Keywords provided by Suzanne Meeks, University of Louisville:
Nursing homes

Additional relevant MeSH terms:
Depressive Disorder
Behavioral Symptoms
Mood Disorders
Mental Disorders