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Treatment for Depression in the Primary Care Setting

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ClinicalTrials.gov Identifier: NCT00055328
Recruitment Status : Completed
First Posted : February 26, 2003
Last Update Posted : September 10, 2013
Sponsor:
Collaborator:
National Institute of Mental Health (NIMH)
Information provided by:
Dartmouth-Hitchcock Medical Center

Brief Summary:
This study will compare a brief form of counseling to usual care for the treatment of minor depression in the primary care setting.

Condition or disease Intervention/treatment Phase
Depression Behavioral: Problem-Solving Treatment for Primary Care Phase 4

Detailed Description:

Minor depression is one of the most common types of depressive disorders seen in primary care. The effectiveness and tolerability of antidepressants in patients with minor depression is unclear, and the development of alternative treatments is necessary.

In the first phase of this study, participants are observed for 4 weeks to identify those most in need of depression-specific treatment. Participants are then exposed to the Problem-Solving Treatment for Primary Care (PST-PC), a six-session behavioral treatment for depression. After 4 weeks, patients who do not respond adequately to the treatment are randomly assigned to either continued PST-PC or to usual care for 9 weeks. Participants are followed for 6 months after the study.


Study Type : Interventional  (Clinical Trial)
Enrollment : 300 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Problem-Solving Treatment for Primary Care Depression
Study Start Date : December 2002
Actual Study Completion Date : December 2006

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Primary care patient at Dartmouth-Hitchcock Medical Center (DHMC)
  • Hamilton Depression Score >= 10 and minor depression at time of entry and after 4 weeks of observation

Exclusion Criteria:

  • Psychosis, Obsessive Compulsive Disorder (OCD), or Post Traumatic Stress Disorder (PTSD)
  • Active substance abuse
  • Receiving treatment for depression

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00055328


Locations
United States, New Hampshire
Dartmouth-Hitchcock Medical Center
Lebanon, New Hampshire, United States, 03756
Sponsors and Collaborators
Dartmouth-Hitchcock Medical Center
National Institute of Mental Health (NIMH)

ClinicalTrials.gov Identifier: NCT00055328     History of Changes
Other Study ID Numbers: R01MH062322 ( U.S. NIH Grant/Contract )
DATR A4-GPS
First Posted: February 26, 2003    Key Record Dates
Last Update Posted: September 10, 2013
Last Verified: August 2008

Additional relevant MeSH terms:
Depression
Depressive Disorder
Behavioral Symptoms
Mood Disorders
Mental Disorders