Therapy for Depressed Elders With Thought Problems
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|ClinicalTrials.gov Identifier: NCT00052091|
Recruitment Status : Completed
First Posted : January 23, 2003
Last Update Posted : January 29, 2018
|Condition or disease||Intervention/treatment||Phase|
|Depression Cognition Disorders||Behavioral: Problem Solving Therapy Behavioral: Brief Supportive Therapy||Phase 3|
Patients who suffer from a combination of major depression and executive dysfunction symptoms often respond poorly to treatment with antidepressants. It is important, therefore, to find effective alternative therapies to treat these symptoms.
Patients are randomly assigned to receive 12 sessions (1 session/week for 12 weeks) of either PST or BST. Following treatment, patients are followed for 6 months to determine functional and clinical outcomes. Depression scales, disability scales, and scales that measure problem solving skills are used to assess patients.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||221 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Single (Outcomes Assessor)|
|Official Title:||PST in Geriatric Depression With Executive Dysfunction|
|Study Start Date :||September 2002|
|Actual Primary Completion Date :||March 2008|
|Actual Study Completion Date :||March 2008|
Experimental: 1 Problem Solving Therapy
12 weekly sessions of problem solving therapy (PST)
Behavioral: Problem Solving Therapy
A 12 week cognitive behavioral intervention for depression that teaches patients a structured approach to solving social problems.
Experimental: 2 Brief Supportive Therapy
12 weekly sessions of brief supportive therapy (BST)
Behavioral: Brief Supportive Therapy
A 12 week intervention for depression that focuses on supporting patients attempts to cope with depression.
- Hamilton Rating Scale for Depression [ Time Frame: Measured at screening, weeks 1 through 12, and week 36 ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00052091
|United States, California|
|University of California at San Francisco|
|San Francisco, California, United States, 94143|
|United States, New York|
|Weill Medical College of Cornell University|
|White Plains, New York, United States, 10605|
|Principal Investigator:||Patricia A. Arean, PhD||University of California at San Francisco|