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Efficacy and Safety of LY451395 in Patients With Probable Alzheimer's Disease

This study has been completed.
Information provided by:
Eli Lilly and Company Identifier:
First received: January 17, 2003
Last updated: July 18, 2006
Last verified: July 2006
Study of an investigational medication for the treatment of Alzheimer's Disease in patients who are not taking Aricept, Reminyl, Exelon.

Condition Intervention Phase
Alzheimer's Disease
Drug: LY451395
Phase 2

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double-Blind
Primary Purpose: Treatment
Official Title: Efficacy and Safety of LY451395 in Patients With Probable Alzheimer's Disease

Resource links provided by NLM:

Further study details as provided by Eli Lilly and Company:

Estimated Enrollment: 200
Study Start Date: November 2002
Estimated Study Completion Date: June 2003

Ages Eligible for Study:   50 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Must have a clinical diagnosis of Alzheimer's Disease
  • Must be at least 50 years of age
  • Must fluently read and speak English
  • Must have a reliable caregiver

Exclusion Criteria:

  • Has serious health problems other than Alzheimer's Disease
  • Cannot swallow whole pills
  • Has had a menstrual period in the last two years
  • Takes insulin for diabetes
  • Has taken Aricept, Reminyl, or Exelon in the last 5 weeks
  Contacts and Locations
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Please refer to this study by its identifier: NCT00051909

United States, California
Beverly Hills, California, United States
Fresno, California, United States
United States, Florida
Boca Raton, Florida, United States
Fort Lauderdale, Florida, United States
Miami Beach, Florida, United States
United States, Massachusetts
Boston, Massachusetts, United States
United States, Oklahoma
Oklahoma City, Oklahoma, United States
Tulsa, Oklahoma, United States
United States, Texas
Wichita Falls, Texas, United States
Sponsors and Collaborators
Eli Lilly and Company
  More Information Identifier: NCT00051909     History of Changes
Other Study ID Numbers: 6764
Study First Received: January 17, 2003
Last Updated: July 18, 2006

Keywords provided by Eli Lilly and Company:
Alzheimer's Disease

Additional relevant MeSH terms:
Alzheimer Disease
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Neurodegenerative Diseases
Neurocognitive Disorders
Mental Disorders processed this record on April 28, 2017