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HORIZON-PFT (Pivotal Fracture Trial) will study the effect of zoledronic acid, given once per year, on the treatment of osteoporosis in women past menopause. Hip and vertebral fractures are the most devastating consequences of osteoporosis. HORIZON-PFT is designed to determine the benefits of zoledronic acid in fracture reduction at both the hip and spine.
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Ages Eligible for Study:
65 Years to 89 Years (Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Female, 65-89 years old
No history of severe liver, kidney or eye disease
Current bisphosphonate users such as Aredia® (pamidronate), Didronel® (etidronate), Fosamax® (alendronate), Actonel® (risedronate), Skelid® (tiludronate)
Using hip protectors
Other protocol-defined inclusion/exclusion criteria may apply.