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Relationship Between Personality and Coping Styles in Bone Marrow Transplant Candidates

This study has been completed.
Information provided by:
National Institutes of Health Clinical Center (CC) Identifier:
First received: October 28, 2002
Last updated: March 3, 2008
Last verified: September 2005

This study will look at how people cope with an upcoming bone marrow transplant and how personality characteristics influence coping styles in stressful medical situations. Personality traits, such as extraversion, optimism and self-esteem have been related to active, problem-focused coping styles, whereas neuroticism has been related to increased psychological distress and denial as a way of coping. Coping styles, in turn, have been related to disease outcome. For example, a fighting spirit and avoidance have been correlated with longer survival, whereas fatalism, anxious preoccupation and feelings of helplessness and hopelessness were related to a poor disease outcome. A better understanding of the relationship between coping styles and personality may help improve supportive care for people undergoing bone marrow transplants. This study will:

  • Explore the relationship between personality traits, coping styles and psychological stress in patients awaiting bone marrow transplantation
  • Identify what coping styles people use to prepare for bone marrow transplantation
  • Identify what personality traits are related to particular coping styles in patients awaiting bone marrow transplantation
  • Identify the relationship between personality factors and level of psychological distress in patients awaiting bone marrow transplantation

Cancer patients 18 years of age and older who are scheduled for bone marrow transplant are eligible for this study.

Participants will fill out pencil-and-paper questionnaires providing demographic information (such as age, gender, marital status, ethnicity, and so forth) and answering questions about their opinions and preferences. The information will be used to assess the participants' personality characteristics, coping styles, and psychological distress. The questionnaires take about 45 to 50 minutes to complete.

Adaptation, Psychological
Bone Marrow Transplantation

Study Type: Observational
Official Title: Exploring the Relationship Between Personality and Coping Styles in Bone Marrow Transplant Candidates

Resource links provided by NLM:

Further study details as provided by National Institutes of Health Clinical Center (CC):

Estimated Enrollment: 57
Study Start Date: October 2002
Estimated Study Completion Date: September 2005
Detailed Description:
Over the last decade, more and more focus has been placed upon the psychological adjustment of patients who have undergone bone marrow transplants (BMT). There have been studies that focused on the coping styles and levels of psychological distress in patients immediately after transplantation. Studies have been done based on a specific point during the process or at multiple points throughout the course of the procedure and still other studies have focused on assessment points several months post transplant. However, very little attention has been focused on patients' psychological functioning prior to transplantation. The purpose of the present study is to examine the relationship between personality traits and coping styles among patients awaiting BMT.

Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No


All patients with diagnosis of cancer and awaiting BMT.

Criteria for participation in the study include a diagnosis of cancer and being actively screened for a CC approved PBSC transplant protocol. The participants will not have undergone the transplant at the time of the evaluation. Participants will be ages 18 and older.


No patients who meet the eligibility criteria will be excluded from the study.

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00048256

United States, Maryland
National Institutes of Health Clinical Center (CC)
Bethesda, Maryland, United States, 20892
Sponsors and Collaborators
National Institutes of Health Clinical Center (CC)
  More Information Identifier: NCT00048256     History of Changes
Other Study ID Numbers: 030028
Study First Received: October 28, 2002
Last Updated: March 3, 2008

Keywords provided by National Institutes of Health Clinical Center (CC):
Personality Assessment
Coping Styles
Psychological Distress
Bone Marrow Transplants
Bone Marrow Transplant processed this record on May 25, 2017