Comment Period Extended to 3/23/2015 for Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials

Clinician Managed Interpersonal Psychotherapy

This study has been completed.
Information provided by:
University of Iowa Identifier:
First received: August 9, 2002
Last updated: September 25, 2013
Last verified: September 2013

This 12-week study will evaluate the effectiveness of Clinician-Managed Interpersonal Psychotherapy (CM-IPT) in treating postpartum depression and will compare CM-IPT to standard IPT.

Condition Intervention Phase
Depression, Postpartum
Behavioral: Standard interpersonal psychotherapy (IPT)
Behavioral: Clinician managed interpersonal psychotherapy (CM-IPT)
Phase 0

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Clinician Managed Interpersonal Psychotherapy

Resource links provided by NLM:

Further study details as provided by University of Iowa:

Primary Outcome Measures:
  • Hamilton Rating Scale for Depression [ Time Frame: Measured at Week 12 ] [ Designated as safety issue: No ]

Enrollment: 140
Study Start Date: September 2001
Study Completion Date: December 2007
Primary Completion Date: December 2007 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1
Participants will receive clinician-managed interpersonal psychotherapy
Behavioral: Clinician managed interpersonal psychotherapy (CM-IPT)
Participants will receive 12 sessions of CM-IPT over 1 year.
Active Comparator: 2
Participants will receive standard interpersonal psychotherapy
Behavioral: Standard interpersonal psychotherapy (IPT)
Participants will receive 12 sessions of IPT over 12 weeks.

Detailed Description:

CM-IPT is delivered in 12 sessions over the course of a year. Standard IPT is delivered in 12 sessions in the first 12 weeks after treatment assignment.


Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes

Inclusion criteria:

  • Women between 8 and 24 weeks postpartum
  • Meet DSM-IV criteria for Major Depression
  • Hamilton Rating Scale for Depression score of 12 or more

Exclusion criteria:

  • Active substance abuse
  • Psychotic disorders
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00043602

United States, Iowa
University of Iowa
Iowa City, Iowa, United States, 52242
Sponsors and Collaborators
University of Iowa
Principal Investigator: Scott P. Stuart, MD University of Iowa
  More Information

No publications provided

Responsible Party: Scott Stuart, University of Iowa Identifier: NCT00043602     History of Changes
Other Study ID Numbers: R01 MH59668, R01MH059668, DSIR 83-ATAS
Study First Received: August 9, 2002
Last Updated: September 25, 2013
Health Authority: United States: Federal Government

Additional relevant MeSH terms:
Depression, Postpartum
Depressive Disorder
Behavioral Symptoms
Mental Disorders
Mood Disorders
Pregnancy Complications
Puerperal Disorders processed this record on March 01, 2015