Farming and Movement Evaluation Study (FAME) - Full Text View

Purpose

The long term goal of this research is to elucidate the cause(s) of Parkinson's disease, with a focus on environmental determinants. We propose to investigate the relationship between Parkinson's disease and exposure to pesticides and other factors by conducting a nested case-control study in the Agricultural Health Study.

Condition
Parkinson's Disease Movement Disorders


Study Type:	Observational
Study Design:	Observational Model: Case Control Time Perspective: Retrospective
Official Title:	Pesticides and Risk in the Agricultural Health Study

Resource links provided by NLM:

Genetics Home Reference related topics: Parkinson disease Perry syndrome

MedlinePlus related topics: Movement Disorders Parkinson's Disease Pesticides

U.S. FDA Resources

Further study details as provided by National Institute of Environmental Health Sciences (NIEHS):


Enrollment:	520
Study Start Date:	April 2001
Primary Completion Date:	July 2011 (Final data collection date for primary outcome measure)

Detailed Description:

The long term goal of this research is to elucidate the cause(s) of Parkinson's disease, with a focus on environmental determinants. We propose to investigate the relationship between Parkinson's disease and exposure to pesticides and other factors by conducting a nested case-control study in the Agricultural Health Study.

The Agricultural Health Study is a cohort study of 52,000 licensed pesticide applicators and 32,000 of their spouses, conducted in North Carolina and Iowa. It is a joint effort of the National Cancer Institute, the National Institute of Environmental Health Sciences, and the US Environmental Protection Agency.

The studies proposed here take full advantage of the Agricultural Health Study. We believe that this work could provide a critical and dramatic next step in furthering our knowledge of environmental determinants of PD, and thereby take us closer to our goal of finding its cause(s)

Eligibility


Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

Subjects will be recruited from members of the Agricultural Health Study cohort.

Contacts and Locations

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00042120

Locations


United States, California
The Parkinson's Institute
Sunnyvale, California, United States, 94089

Sponsors and Collaborators

National Institute of Environmental Health Sciences (NIEHS)

Investigators


Principal Investigator:	Caroline M Tanner	The Parkinson's Institute

More Information

No publications provided


Responsible Party:	Caroline M. Tanner, MD, Ph.D., The Parkinson's Institute
ClinicalTrials.gov Identifier:	NCT00042120 History of Changes
Obsolete Identifiers:	NCT00342914
Other Study ID Numbers:	10803-CP-001
Study First Received:	July 24, 2002
Last Updated:	September 26, 2014
Health Authority:	United States: Federal Government

Keywords provided by National Institute of Environmental Health Sciences (NIEHS):


Parkinson's disease Movement Disorders Epidemiological Study

Additional relevant MeSH terms:


Movement Disorders Parkinson Disease Basal Ganglia Diseases Brain Diseases	Central Nervous System Diseases Nervous System Diseases Neurodegenerative Diseases Parkinsonian Disorders

ClinicalTrials.gov processed this record on March 03, 2015