Farming and Movement Evaluation Study (FAME) (FAME)
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ClinicalTrials.gov Identifier: NCT00042120 |
Recruitment Status :
Completed
First Posted : July 26, 2002
Last Update Posted : September 29, 2014
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Condition or disease |
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Parkinson's Disease Movement Disorders |
The long term goal of this research is to elucidate the cause(s) of Parkinson's disease, with a focus on environmental determinants. We propose to investigate the relationship between Parkinson's disease and exposure to pesticides and other factors by conducting a nested case-control study in the Agricultural Health Study.
The Agricultural Health Study is a cohort study of 52,000 licensed pesticide applicators and 32,000 of their spouses, conducted in North Carolina and Iowa. It is a joint effort of the National Cancer Institute, the National Institute of Environmental Health Sciences, and the US Environmental Protection Agency.
The studies proposed here take full advantage of the Agricultural Health Study. We believe that this work could provide a critical and dramatic next step in furthering our knowledge of environmental determinants of PD, and thereby take us closer to our goal of finding its cause(s)
Study Type : | Observational |
Actual Enrollment : | 520 participants |
Observational Model: | Case-Control |
Time Perspective: | Retrospective |
Official Title: | Pesticides and Risk in the Agricultural Health Study |
Study Start Date : | April 2001 |
Actual Primary Completion Date : | July 2011 |


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Ages Eligible for Study: | 18 Years and older (Adult, Older Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
- Subjects will be recruited from members of the Agricultural Health Study cohort.

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00042120
United States, California | |
The Parkinson's Institute | |
Sunnyvale, California, United States, 94089 |
Principal Investigator: | Caroline M Tanner | The Parkinson's Institute |
Responsible Party: | Caroline M. Tanner, MD, Ph.D., The Parkinson's Institute |
ClinicalTrials.gov Identifier: | NCT00042120 |
Obsolete Identifiers: | NCT00342914 |
Other Study ID Numbers: |
10803-CP-001 |
First Posted: | July 26, 2002 Key Record Dates |
Last Update Posted: | September 29, 2014 |
Last Verified: | August 2009 |
Parkinson's disease Movement Disorders Epidemiological Study |
Parkinson Disease Movement Disorders Parkinsonian Disorders Basal Ganglia Diseases Brain Diseases |
Central Nervous System Diseases Nervous System Diseases Synucleinopathies Neurodegenerative Diseases |