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Farming and Movement Evaluation Study (FAME) (FAME)

This study has been completed.
Sponsor:
Information provided by:
National Institute of Environmental Health Sciences (NIEHS)
ClinicalTrials.gov Identifier:
NCT00042120
First received: July 24, 2002
Last updated: September 26, 2014
Last verified: August 2009
History of Changes
  Purpose
The long term goal of this research is to elucidate the cause(s) of Parkinson's disease, with a focus on environmental determinants. We propose to investigate the relationship between Parkinson's disease and exposure to pesticides and other factors by conducting a nested case-control study in the Agricultural Health Study.

Condition
Parkinson's Disease
Movement Disorders

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Retrospective
Official Title: Pesticides and Risk in the Agricultural Health Study

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by National Institute of Environmental Health Sciences (NIEHS):
Enrollment: 520
Study Start Date: April 2001
Primary Completion Date: July 2011 (Final data collection date for primary outcome measure)
Detailed Description:

The long term goal of this research is to elucidate the cause(s) of Parkinson's disease, with a focus on environmental determinants. We propose to investigate the relationship between Parkinson's disease and exposure to pesticides and other factors by conducting a nested case-control study in the Agricultural Health Study.

The Agricultural Health Study is a cohort study of 52,000 licensed pesticide applicators and 32,000 of their spouses, conducted in North Carolina and Iowa. It is a joint effort of the National Cancer Institute, the National Institute of Environmental Health Sciences, and the US Environmental Protection Agency.

The studies proposed here take full advantage of the Agricultural Health Study. We believe that this work could provide a critical and dramatic next step in furthering our knowledge of environmental determinants of PD, and thereby take us closer to our goal of finding its cause(s)

  Eligibility
Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Subjects will be recruited from members of the Agricultural Health Study cohort.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00042120

Locations
United States, California
The Parkinson's Institute
Sunnyvale, California, United States, 94089
Sponsors and Collaborators
National Institute of Environmental Health Sciences (NIEHS)
Investigators
Principal Investigator: Caroline M Tanner The Parkinson's Institute
  More Information

Responsible Party: Caroline M. Tanner, MD, Ph.D., The Parkinson's Institute
ClinicalTrials.gov Identifier: NCT00042120     History of Changes
Obsolete Identifiers: NCT00342914
Other Study ID Numbers: 10803-CP-001 
Study First Received: July 24, 2002
Last Updated: September 26, 2014
Health Authority: United States: Federal Government

Keywords provided by National Institute of Environmental Health Sciences (NIEHS):
Parkinson's disease
Movement Disorders
Epidemiological Study

Additional relevant MeSH terms:
Parkinson Disease
Movement Disorders
Parkinsonian Disorders
Basal Ganglia Diseases
 Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Neurodegenerative Diseases

ClinicalTrials.gov processed this record on September 26, 2016